CDK2AP2 Antibody
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货号:CSB-PA005063LA01HU
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规格:¥440
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促销:
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图片:
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其他:
产品详情
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产品名称:Rabbit anti-Homo sapiens (Human) CDK2AP2 Polyclonal antibody
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Uniprot No.:O75956
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基因名:CDK2AP2
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别名:CDK2AP2 antibody; DOC1RCyclin-dependent kinase 2-associated protein 2 antibody; CDK2-associated protein 2 antibody; DOC-1-related protein antibody; DOC-1R antibody
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宿主:Rabbit
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反应种属:Human
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免疫原:Recombinant Human Cyclin-dependent kinase 2-associated protein 2 protein (1-126AA)
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免疫原种属:Homo sapiens (Human)
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标记方式:Non-conjugated
本页面中的产品,CDK2AP2 Antibody (CSB-PA005063LA01HU),的标记方式是Non-conjugated。对于CDK2AP2 Antibody,我们还提供其他标记。见下表:
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克隆类型:Polyclonal
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抗体亚型:IgG
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纯化方式:>95%, Protein G purified
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浓度:It differs from different batches. Please contact us to confirm it.
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保存缓冲液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
产品提供形式:Liquid
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应用范围:ELISA, IHC
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推荐稀释比:
Application Recommended Dilution IHC 1:20-1:200 -
Protocols:
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储存条件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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靶点详情
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功能:Plays a role in regulating the self-renewal of embryonic stem cells (ESCs) and in maintaining cell survival during terminal differentiation of ESCs. Regulates microtubule organization of metaphase II oocytes. Inhibits cell cycle G1/S phase transition by repressing CDK2 expression and activation; represses CDK2 activation by inhibiting its interaction with cyclin E and A.
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基因功能参考文献:
- Our findings suggest that alteration of p16, p14, p27, p21, and p53 status may contribute to carcinogenesis and the clinical behavior of HPV-negative adenocarcinoma of the uterine cervix PMID: 25675191
- antitumor effects of DOC-1R may be mediated by negatively regulating G1 phase progression and G1/S transition through inhibiting CDK2 expression and activation PMID: 23781148
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亚细胞定位:Cytoplasm. Nucleus.
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蛋白家族:CDK2AP family
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组织特异性:Ubiquitous.
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数据库链接:
HGNC: 30833
KEGG: hsa:10263
STRING: 9606.ENSP00000301488
UniGene: Hs.523835
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