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CDK2AP2 Antibody

  • 货号:
    CSB-PA005063LA01HU
  • 规格:
    ¥440
  • 促销:
    小规格抗体限时一口价
  • 图片:
    • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA005063LA01HU at dilution of 1:100
  • 其他:

产品详情

  • 产品名称:
    Rabbit anti-Homo sapiens (Human) CDK2AP2 Polyclonal antibody
  • Uniprot No.:
    O75956
  • 基因名:
    CDK2AP2
  • 别名:
    CDK2AP2 antibody; DOC1RCyclin-dependent kinase 2-associated protein 2 antibody; CDK2-associated protein 2 antibody; DOC-1-related protein antibody; DOC-1R antibody
  • 宿主:
    Rabbit
  • 反应种属:
    Human
  • 免疫原:
    Recombinant Human Cyclin-dependent kinase 2-associated protein 2 protein (1-126AA)
  • 免疫原种属:
    Homo sapiens (Human)
  • 标记方式:
    Non-conjugated

    本页面中的产品,CDK2AP2 Antibody (CSB-PA005063LA01HU),的标记方式是Non-conjugated。对于CDK2AP2 Antibody,我们还提供其他标记。见下表:

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA005063LB01HU CDK2AP2 Antibody, HRP conjugated ELISA
    FITC CSB-PA005063LC01HU CDK2AP2 Antibody, FITC conjugated
    Biotin CSB-PA005063LD01HU CDK2AP2 Antibody, Biotin conjugated ELISA
  • 克隆类型:
    Polyclonal
  • 抗体亚型:
    IgG
  • 纯化方式:
    >95%, Protein G purified
  • 浓度:
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式:
    Liquid
  • 应用范围:
    ELISA, IHC
  • 推荐稀释比:
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols:
  • 储存条件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能:
    Plays a role in regulating the self-renewal of embryonic stem cells (ESCs) and in maintaining cell survival during terminal differentiation of ESCs. Regulates microtubule organization of metaphase II oocytes. Inhibits cell cycle G1/S phase transition by repressing CDK2 expression and activation; represses CDK2 activation by inhibiting its interaction with cyclin E and A.
  • 基因功能参考文献:
    1. Our findings suggest that alteration of p16, p14, p27, p21, and p53 status may contribute to carcinogenesis and the clinical behavior of HPV-negative adenocarcinoma of the uterine cervix PMID: 25675191
    2. antitumor effects of DOC-1R may be mediated by negatively regulating G1 phase progression and G1/S transition through inhibiting CDK2 expression and activation PMID: 23781148
  • 亚细胞定位:
    Cytoplasm. Nucleus.
  • 蛋白家族:
    CDK2AP family
  • 组织特异性:
    Ubiquitous.
  • 数据库链接:

    HGNC: 30833

    KEGG: hsa:10263

    STRING: 9606.ENSP00000301488

    UniGene: Hs.523835