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CCDC106 Antibody

  • 货号：
    CSB-PA863135LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: CCDC106 antibody at 4µg/ml + Mouse brain tissue
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 33 kDa
      Observed band size: 33 kDa
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA863135LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) CCDC106 Polyclonal antibody
  • Uniprot No.：
    Q9BWC9
  • 基因名：
    CCDC106
  • 别名：
    CC106_HUMAN antibody; Ccdc106 antibody; Coiled-coil domain-containing protein 106 antibody; HSU79303 antibody; Protein predicted by clone 23882 antibody; ZNF581 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Recombinant Human Coiled-coil domain-containing protein 106 protein (1-280AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，CCDC106 Antibody (CSB-PA863135LA01HU)，的标记方式是Non-conjugated。对于CCDC106 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA863135LB01HU CCDC106 Antibody, HRP conjugated ELISA
    FITC CSB-PA863135LC01HU CCDC106 Antibody, FITC conjugated
    Biotin CSB-PA863135LD01HU CCDC106 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Promotes the degradation of p53/TP53 protein and inhibits its transactivity.
  • 基因功能参考文献：
    1. Our studies revealed that CCDC106 is associated with non-small cell lung cancer progression and unfavorable prognosis. CCDC106 enhanced Cyclin A2 and Cyclin B1 expression and promoted A549 and H1299 cell proliferation, which depended on AKT signaling. These results suggest that CCDC106 may be a novel target for lung cancer treatment. PMID: 28460455
    2. CCDC106 promotes the degradation of p53 protein and inhibits its transactivity. PMID: 20159018
  • 亚细胞定位：
    Nucleus. Note=Colocalizes with p53/TP53.
  • 数据库链接：

    HGNC: 30181

    OMIM: 613478

    KEGG: hsa:29903

    UniGene: Hs.82482