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C1QTNF1 Antibody

  • 货号：
    CSB-PA003646GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q9BXJ1
  • 基因名：
    C1QTNF1
  • 别名：
    C1q and tumor necrosis factor related protein 1 antibody; C1QT1_HUMAN antibody; C1QTNF1 antibody; Complement C1q tumor necrosis factor related protein 1 antibody; Complement C1q tumor necrosis factor-related protein 1 antibody; CTRP 1 antibody; CTRP1 antibody; FLJ90694 antibody; G protein coupled receptor interacting protein 1 antibody; G protein-coupled receptor-interacting protein antibody; GIP antibody; ZSIG37 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human C1QTNF1
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 基因功能参考文献：
    1. CTRP1 has a role in linking dysregulation of lipid metabolism and inflammatory responses in macrophages PMID: 27175610
    2. High serum CTRP1 level is associated with Type 2 diabetes mellitus. PMID: 28207876
    3. In cultured endothelial cells, treatment of CTRP1 led to increased permeability to fluorescent-labelled dextran and apparent formation of paracellular holes as observed after disturbed flow exposure, which was evidently reduced in the presence of a CTRP1-specific neutralizing antibody. PMID: 28625919
    4. Increased serum CTRP 1 levels were closely associated with the prevalence and severity of CAD, it might be regarded as a marker for myocardial infarction. PMID: 27169633
    5. the strong association of CTRP1 with insulin resistance in NAFLD PMID: 25767880
    6. The levels of circulating CTRP1 are associated with coronary artery disease in men. PMID: 24945145
    7. The variation of plasma CTRP-1 and IL-6 concentrations may play an important role in reflecting the degree of inflammation in CHD and the severity of coronary arterial atherosclerosis. PMID: 25635749
    8. Increased plasma CTRP1 was independently associated with type 2 diabetes. Profiling of plasma adipokines such as CTRP1 is particularly important to obtain a greater understanding of their contribution to the type 2 diabetic state. PMID: 24965225
    9. CTRP1 is a novel adipokine associated with type 2 diabetes mellitus in humans. PMID: 24827430
    10. CTRP1 level was significantly higher in subjects with metabolic syndrome compared to healthy subjects. PMID: 23000311
    11. The review describes the potential role of C1qTNF1 as an intracellular regulator of signal transduction PMID: 16386877
    12. molecular cloning, gene expression, and subcellular localization of GIP PMID: 12409230
    13. These findings indicate that CTRP1 expression may be associated with a low-grade chronic inflammation status in adipose tissues. PMID: 16806199
    14. CTRP1 enhances the production of aldosterone. CTRP1 was highly expressed in obese subjects as well as up-regulated in hypertensive patients, CTRP1 may be a newly identified molecular link between obesity and hypertension. PMID: 18171693
    15. CTRP1 may be considered a novel adipokine, providing an important framework to further address the physiological functions and mechanisms of the action of this family of secreted glycoproteins in normal and disease states. PMID: 18783346

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  • 亚细胞定位：
    Secreted.
  • 数据库链接：

    HGNC: 14324

    OMIM: 610365

    KEGG: hsa:114897

    STRING: 9606.ENSP00000340864

    UniGene: Hs.201398