Your Good Partner in Biology Research

  1. Home
  2. 抗体
  3. 多克隆抗体
  4. AMT Antibody

AMT Antibody

  • 货号：
    CSB-PA001684LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in: A549 whole cell lysate, Mouse brain tissue
      All lanes: AMT antibody at 3.5µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 44, 38, 40, 42 kDa
      Observed band size: 44 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) AMT Polyclonal antibody
  • Uniprot No.：
    P48728
  • 基因名：
    AMT
  • 别名：
    Aminomethyltransferase (glycine cleavage system protein T) antibody; Aminomethyltransferase antibody; AMT antibody; GCE antibody; GCST antibody; GCST_HUMAN antibody; GCVT antibody; Glycine cleavage system T protein antibody; mitochondrial antibody; NKH antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Recombinant Human Aminomethyltransferase, mitochondrial protein (180-260AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，AMT Antibody (CSB-PA001684LA01HU)，的标记方式是Non-conjugated。对于AMT Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA001684LB01HU AMT Antibody, HRP conjugated ELISA
    FITC CSB-PA001684LC01HU AMT Antibody, FITC conjugated
    Biotin CSB-PA001684LD01HU AMT Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    The glycine cleavage system catalyzes the degradation of glycine.
  • 基因功能参考文献：
    1. The position and frequency of the breakpoint for CNVs correlated with intron size and presence of Alu elements. Missense mutations, most often recurring, were the most common type of disease-causing mutation in AMT PMID: 27362913
    2. Data indicate no mutation was found in glycine cleavage system protein-H (GCSH) and suggest that mutations in both glycine decarboxylase (GLDC) and aminomethyltransferase (AMT) are the main cause of glycine encephalopathy in Malaysian population. PMID: 25231368
    3. Two unique non-synonymous changes were identified in the AMT gene in patients with neural tube defects. PMID: 22171071
    4. x-ray crystallographic structure of human T-protein of glycine cleavage system PMID: 16051266
  • 相关疾病：
    Non-ketotic hyperglycinemia (NKH)
  • 亚细胞定位：
    Mitochondrion.
  • 蛋白家族：
    GcvT family
  • 数据库链接：

    HGNC: 473

    OMIM: 238310

    KEGG: hsa:275

    STRING: 9606.ENSP00000273588

    UniGene: Hs.102