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ACOX2 Antibody

  • 货号：
    CSB-PA001173GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q99424
  • 基因名：
  • 别名：
    12-alpha-trihydroxy-5-beta-cholestanoyl-CoA 24-hydroxylase antibody; 12-alpha-trihydroxy-5-beta-cholestanoyl-CoA oxidase antibody; 3 alpha 7 alpha 12 alpha trihydroxy 5 beta cholestanoyl CoA oxidase antibody; 3 alpha 7 alpha12 alpha trihydroxy 5 beta cholestanoyl CoA 24 hydroxylase antibody; 3-alpha antibody; 7-alpha antibody; ACOX 2 antibody; ACOX2 antibody; ACOX2_HUMAN antibody; Acyl CoA oxidase 2 antibody; Acyl Coenzyme A oxidase 2 antibody; Acyl Coenzyme A oxidase 2 branched chain antibody; Acyl coenzyme A oxidase 2 peroxisomal antibody; BCOX antibody; BRCACOX antibody; BRCOX antibody; Peroxisomal acyl-coenzyme A oxidase 2 antibody; Peroxisomal branched chain acyl CoA oxidase antibody; THCA CoA oxidase antibody; THCA-CoA oxidase antibody; THCCox antibody; Trihydroxycoprostanoyl CoA oxidase antibody; Trihydroxycoprostanoyl-CoA oxidase antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human ACOX2
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,IHC,IF
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Oxidizes the CoA esters of the bile acid intermediates di- and tri-hydroxycholestanoic acids. Capable of oxidizing short as well as long chain 2-methyl branched fatty acids.
  • 基因功能参考文献：
    1. We have identified by the first time in a young patient and his only sister a familiar genetic defect of an enzyme called ACOX2, which participates in the transformation of cholesterol into bile acids as a cause of increased serum transaminases in the absence of any other symptomatology. PMID: 27884763
    2. Results found an ACOX2 variant present in a subset of human breast cancers and associated with improved outcome ER+ tumors suggesting it as a potential novel therapeutic biomarker in ER+ breast tumors. PMID: 26183823
    3. Our results suggest that downregulation of ACOX2 is a shared risk factor for PE and CVD. PMID: 21343950
  • 相关疾病：
    Congenital bile acid synthesis defect 6 (CBAS6)
  • 亚细胞定位：
    Peroxisome.
  • 蛋白家族：
    Acyl-CoA oxidase family
  • 组织特异性：
    Present in all tissues tested: heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Most abundant in heart, liver and kidney.
  • 数据库链接：

    HGNC: 120

    OMIM: 601641

    KEGG: hsa:8309

    STRING: 9606.ENSP00000307697

    UniGene: Hs.444959