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ACBD5 Antibody

  • 货号：
    CSB-PA725893HA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: ACBD5 antibody at 2µg/ml + Hela whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 61, 55, 59, 47 kDa
      Observed band size: 61 kDa
  • 其他：

产品详情

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) ACBD5 Polyclonal antibody
  • Uniprot No.：
    Q5T8D3
  • 基因名：
    ACBD5
  • 别名：
    Acbd5 antibody; ACBD5_HUMAN antibody; Acyl CoA binding domain containing 5 antibody; Acyl CoA binding domain containing protein 5 antibody; Acyl Coenzyme A binding domain containing 5 antibody; Acyl-CoA-binding domain-containing protein 5 antibody; DKFZp434A2417 antibody; Endozepine related protein antibody; KIAA1996 antibody; Membrane associated diazepam binding inhibitor antibody; OTTHUMP00000019362 antibody; OTTHUMP00000019363 antibody; OTTHUMP00000019364 antibody; OTTHUMP00000019365 antibody; RP11-85G18.5 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Recombinant Human Acyl-CoA-binding domain-containing protein 5 protein (1-461AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，ACBD5 Antibody (CSB-PA725893HA01HU)，的标记方式是Non-conjugated。对于ACBD5 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA725893HB01HU ACBD5 Antibody, HRP conjugated ELISA
    FITC CSB-PA725893HC01HU ACBD5 Antibody, FITC conjugated
    Biotin CSB-PA725893HD01HU ACBD5 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:1000-1:5000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy. Binds medium- and long-chain acyl-CoA esters.
  • 基因功能参考文献：
    1. ACBD5 captures VLC-CoAs on the cytosolic side of the peroxisomal membrane so that the transport of VLC-CoAs into peroxisomes and subsequent beta-oxidation thereof can proceed efficiently. PMID: 27899449
    2. ACBD5-VAPB interaction regulates peroxisome-endoplasmic reticulum associations. Loss of PO-ER association perturbs PO membrane expansion and increases PO movement. PMID: 28108524
    3. VAP-ACBD5-mediated contact between the endoplasmic reticulum and peroxisomes mediate organelle maintenance and lipid homeostasis. PMID: 28108526
    4. Findings suggest that the ACBD5-RET rearrangement is causatively involved in the development of papillary thyroid cancer. PMID: 25175022
    5. Yeast Atg37, which is homologous to human ACBD5, is involved in autophagy of peroxisomes. PMID: 24905344
    6. A mutation in the acyl-coenzyme A binding domain-containing protein 5 gene (ACBD5 ) may have a role in autosomal dominant thrombocytopenia PMID: 20626622

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  • 亚细胞定位：
    Peroxisome membrane; Single-pass membrane protein.
  • 蛋白家族：
    ATG37 family
  • 数据库链接：

    HGNC: 23338

    OMIM: 616618

    KEGG: hsa:91452

    STRING: 9606.ENSP00000379568

    UniGene: Hs.530597