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ABCA6 Antibody

  • 货号：
    CSB-PA000780
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of 293 cells using ABCA6 Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    Q8N139
  • 基因名：
    ABCA6
  • 别名：
    ABC transporter ABCA6 antibody; ABCA 6 antibody; ABCA6 antibody; ABCA6_HUMAN antibody; ATP binding cassette A6 antibody; ATP binding cassette sub family A (ABC1) member 6 antibody; ATP binding cassette sub family A member 6 antibody; ATP-binding cassette sub-family A member 6 antibody; EST155051 antibody; FLJ43498 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from the C-terminal region of Human ABCA6.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:40000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Probable transporter which may play a role in macrophage lipid transport and homeostasis.
  • 基因功能参考文献：
    1. A rare missense variant in ABCA6 (rs77542162, p.Cys1359Arg, frequency 0.034), found in a Dutch population, is predicted to be deleterious with respect to blood cholesterol levels. PMID: 25751400
    2. These data provide evidence for an essential role of FoxO proteins in the transcription of ABCA6 in human vascular endothelial cells. PMID: 24028821
  • 亚细胞定位：
    Golgi apparatus membrane; Multi-pass membrane protein.
  • 蛋白家族：
    ABC transporter superfamily, ABCA family
  • 组织特异性：
    Widely expressed with higher expression in liver.
  • 数据库链接：

    HGNC: 36

    OMIM: 612504

    KEGG: hsa:23460

    STRING: 9606.ENSP00000284425

    UniGene: Hs.709514