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  4. Rat Collagen alpha-1(I) chain (COL1A1) ELISA kit

Rat Collagen alpha-1(I) chain (COL1A1) ELISA kit

  • 中文名称：
    大鼠I型胶原α1链 (COL1A1)酶联免疫试剂盒
  • 货号：
    CSB-E12732r
  • 规格：
    96T/48T
  • 价格：
    ￥3800/￥2500
  • 其他：

产品详情

  • 产品描述：

    The rat collagen alpha-1 chain (COL1A1) ELISA Kit is used to quantitatively measure rat COL1A1 concentrations in serum, plasma, or tissue homogenates. It performs well in important characteristics, including sensitivity and specificity. This assay is based on the sandwich ELISA mechanism and enzyme-substrate chromogenic reaction. The solution color develops proportionally to the amount of COL1A1 in the sample. And the intensity of the color can be measured at 450 nm via a microplate reader.

    COL1A1 is a major component of collagen type I. It has recently been found that COL1A1 is overexpressed in a variety of tumor tissues and cells such as hepatocellular carcinoma (HCC). Mutations in COL1A1 can cause collagen-related diseases, including autosomal dominant osteogenesis imperfecta (OI) and the rare arthrochalasis subtype of Ehlers-Danlos syndrome (EDS). Liu J et al. have demonstrated that a high level of COL1A1 is indicative of a more aggressive cellular behavior and poorer prognosis in patients with breast cancer, especially in those with ER+ breast cancer.

  • 别名：
    COL1A1Collagen alpha-1(I) chain ELISA kit; Alpha-1 type I collagen ELISA kit; Fragment ELISA kit
  • 缩写：
  • Uniprot No.：
  • 种属：
    Rattus norvegicus (Rat)
  • 样本类型：
    serum, plasma, tissue homogenates
  • 检测范围：
    0.156 ng/mL-10 ng/mL
  • 灵敏度：
    0.039 ng/mL
  • 反应时间：
    1-5h
  • 样本体积：
    50-100ul
  • 检测波长：
    450 nm
  • 研究领域：
    Signal Transduction
  • 测定原理：
    quantitative
  • 测定方法：
    Sandwich
  • 数据处理：
  • 货期：
    3-5 working days

产品评价

靶点详情

  • 功能：
    Type I collagen is a member of group I collagen (fibrillar forming collagen).
  • 亚细胞定位：
    Secreted, extracellular space, extracellular matrix.
  • 蛋白家族：
    Fibrillar collagen family
  • 组织特异性：
    Forms the fibrils of tendon, ligaments and bones. In bones the fibrils are mineralized with calcium hydroxyapatite.
  • 数据库链接：

    UniGene: Ocu.3445