Rat Catalase (CAT) ELISA kit

1. These results indicate that stress conditions most probably altered the cell redox equilibrium, thus influencing the antioxidant response in brain cortex. PMID: 29847079
2. fenofibrate almost completely abolished GM-induced reactive oxygen species generation, which seemed to be mediated at least in part by the restoration of the expression of PPARalphadependent antioxidant enzymes, including catalase and superoxide dismutase (SOD)-1. PMID: 28290603
3. These results indicate that CAT expression is significantly decreased in the hippocampi of aged animals and decreased CAT expression may be closely associated with aging. PMID: 27221506
4. Catalase promoter region (-185 to +52) that contains binding sites for C/EBP-beta showed an augmentation in the methylation level along with a change in methylation pattern of CpG islands in response to PTU treatment PMID: 26459835
5. Data show that nuclear factor erythroid 2-related factor (Nrf2), superoxide dismutase Sod1 and catalase antioxidant systems are downregulated in isolated arteries and vascular smooth muscle cells from stroke-prone spontaneously hypertensive rats (SHRSP). PMID: 26503970
6. mitochondria-targeted antioxidant SkQ1 (50 nmol/kg during 5 days) significantly increased the mRNA levels of Nrf2 transcription factor and Nrf2-induced genes encoding antioxidant enzymes SOD1, SOD2, CAT, and GPx4 in rat peripheral blood leukocytes. PMID: 26071777
7. Targeted mass spectrometry for the analysis of nutritive modulation of catalase and heme oxygenase-1 expression. PMID: 25639505
8. Decrease in Sirtuin1 (SIRT1) and nuclear factor erythroid 2-related factor (Nrf2) and increase in nuclear factor kappa B (NFkappaB) gene expression in diabetes were associated with a decrease in CAT and GPx mRNA expression. PMID: 24740756
9. Coronary resistance regulation seems to be more dependent on the hydrogen peroxide that is maintained at low levels by increased catalase activity. PMID: 24669281
10. Catalase was found to participate in lead-induced alcohol intake and is elevated in blood following lead exposure. PMID: 23808586
11. The marked increased in alcohol intake that follows an alcohol deprivation period is mediated by acetaldehyde generated in the brain by the action of catalase. PMID: 23527889
12. Results suggest that the effects of estrogen on the cell-mediated immune responses are mediated through specific estrogen receptors alpha and beta and antioxidant enzymes superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx). PMID: 23911387
13. The content of catalase protein in mitochondrial extract increased with aging. PMID: 22683338
14. Ornithine alpha-ketoglutarate modulates the levels of antioxidants glutathione peroxidase, superoxide dismutase and catalase, as well as lipid peroxidation products in ammonium acetate treated rats PMID: 22905402
15. The increased expression of antioxidant catalase, specifically in hippocampal neurons, will provide protection from age-related cognitive decline. PMID: 21942371
16. Ang II inhibited catalase (CAT) and peroxisome proliferator-activated receptor gamma (PPAR gamma) protein and mRNA expressions. PMID: 21295034
17. Chronic psychosocial isolation attenuated peroxide-metabolizing enzymes, CAT and GPx, and decreased GLR activity. PMID: 20063054
18. catalase activities in liver and kidney of diabetic male or female rats were significantly lower than in non-diabetic rats but the reduction was more pronounced in diabetic female rats. PMID: 20830981
19. This protein has been found differentially expressed in the lumbar spinal cord from rats submitted to peripheral lesion during neonatal period. PMID: 20387083
20. endogenous PGC-1 alpha is a negative regulator of vascular hypertrophy by up-regulating catalase expression and thus reducing reactive oxygen species levels PMID: 19940161
21. No significant differences in superoxide dismutase and catalase activities, but MDA was decreased by ghrelin on day 10. Evidence for antioxidant properties of ghrelin in rat testis. PMID: 19891630
22. in addition to transrepression of proinflammatory transcription factors, peroxisome proliferator-activated receptor-gamma may also be modulating catalase expression PMID: 12456800
23. Levels of Cat mRNA were significantly reduced in congestive heart failure following myocardial infarction. PMID: 14575298
24. Catalase activities decreased in the liver and heart of rats with hypothyroidism PMID: 14624470
25. Over-expression catalase genes in primary hippocampal or cortical cultures resulted in increased enzymatic activity of the cognate protein. PMID: 14713308
26. Changes in post-brain injury/intervention levels of NGF and activity of three major enzymes responsible for ROS scavenging, catalase (CAT), glutathione peroxidase (GPx) and superoxide dismutase (SOD), was determined in the hippocampus PMID: 15287906
27. Medroxyprogesterone acetate and idarubicin both inhibit blood levels of this enzyme PMID: 15372991
28. generation of H(2)O(2) and expression of CAT are coordinated and indicative of epidermal differentiation as well as of the role of CAT in repairing redox damage PMID: 15734284
29. influence of gender upon activities of catalase (CAT), glutathione peroxidase (GPX), and superoxide dismutase (SOD) in hypertension PMID: 15773229
30. catalase and glutathione peroxidase are downregulated in renal insufficiency PMID: 15777843
31. rats subjected to ovariectomy presented a significant increase in brain Na+, K+-ATPase, AChE and CAT activities, but did not change the oxidative stress parameters PMID: 15869839
32. Multiple complex formation of C/EBP-beta regulates transcription in the TATA-less catalase promoter. PMID: 16223488
33. psychological stressor induces a "priming" effect specifically on the CuZnSOD and CAT activity PMID: 16238459
34. Results suggest that amphetamine exposure is associated with an imbalance between superoxide dismutase and catalase activity in the prefrontal cortex, hippocampus and striatum. PMID: 16770742
35. Ischemic attack causes a rapid response in hippocampal tissue as well as in the cerebrospinal fluid, represented by an increase in the activity of endogenous antioxidant enzymes SOD and CAT PMID: 17215005
36. catalase is a major participant in the defense of 36B10 glioma cells against oxidative stress PMID: 17320761
37. mRNA and protein expressions of superoxide dismutase (SOD) and catalase increase after ischemia (I) and reperfusion (R) of the rat liver. PMID: 17524832
38. Nimesulide decreased Cat activity significantly in rats subjected to ischemia. PMID: 17564305
39. observations are compatible with the presence of endogenous heme-containing catalase with an activity of 825 +/- 15 units, which contributes to mitochondrial protection against endogenous or exogenous H2O2 PMID: 17576767
40. Findings strongly support the assumption that catalase plays a significant role in acetaldehyde formation directly in the rat brain. PMID: 17597213
41. Even though mRNA expressions of both catalase and Cu-Zn SOD were not changed, the protein levels increased in parallel to activities in the case of another antioxidant, alpha-lipoic acid. PMID: 18008141
42. Results describe the activity of superoxide dismutase and catalase at different ages following methylphenidate treatment in young rats. PMID: 18049893
43. Elevated catalase levels in hearts of long-term type 1 diabetic rats signals improved recovery of postischemic cardiac function and reduced reperfusion arrhythmia. PMID: 18430061
44. Reduced availability of reactive oxygen species by catalase is a key component of neuroprotection against various toxic stimuli PMID: 19302986

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KEGG: rno:24248

STRING: 10116.ENSRNOP00000011230

UniGene: Rn.3001