Pig Hepcidin(HAMP) ELISA kit

文献引用 (1) 说明书下载

产品详情

产品描述：

This Pig HAMP ELISA Kit was designed for the quantitative measurement of Pig HAMP protein in serum, plasma, tissue homogenates. It is a Sandwich ELISA kit, its detection range is 9.38 ng/mL-600 ng/mL and the sensitivity is 2.34 ng/mL.
别名：

HAMP ELISA Kit; Hepcidin ELISA Kit
缩写：

HAMP
Uniprot No.：

Q8MJ80
种属：

Sus scrofa (Pig)
样本类型：

serum, plasma, tissue homogenates
检测范围：

9.38 ng/mL-600 ng/mL
灵敏度：

2.34 ng/mL
反应时间：

1-5h
样本体积：

50-100ul
检测波长：

450 nm
研究领域：

Cardiovascular
测定原理：

quantitative
测定方法：

Sandwich
数据处理：

ELISA操作视频及标曲绘制软件下载
货期：

3-5 working days

功能：

Liver-produced hormone that constitutes the main circulating regulator of iron absorption and distribution across tissues. Acts by promoting endocytosis and degradation of ferroportin/SLC40A1, leading to the retention of iron in iron-exporting cells and decreased flow of iron into plasma. Controls the major flows of iron into plasma: absorption of dietary iron in the intestine, recycling of iron by macrophages, which phagocytose old erythrocytes and other cells, and mobilization of stored iron from hepatocytes.; Has strong antimicrobial activity against E.coli ML35P N.cinerea and weaker against S.epidermidis, S.aureus and group b streptococcus bacteria. Active against the fungus C.albicans. No activity against P.aeruginosa.
基因功能参考文献：
1. this study demonstrates that urine hepcidin-25 concentrations strongly correlate with hepatic hepcidin mRNA abundance, plasma hepcidin-25 levels, iron transferrin saturation and non-heme liver iron levels. PMID: 26323096
2. Data suugest that hepcidin might had antiinflammatory function and is a candidate regulator of the cross-talk between iron regulation and inflammation. PMID: 25774043
3. report the full-length cDNA sequences of porcine hepcidin and liver-expressed antimicrobial peptide-2 (LEAP-2) PMID: 16051358
亚细胞定位：

Secreted.
蛋白家族：

Hepcidin family
数据库链接：

KEGG: ssc:397207

STRING: 9823.ENSSSCP00000028422

UniGene: Ssc.376