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  4. Mouse Vascular cell adhesion molecule 1,VCAM-1 ELISA kit

Mouse Vascular cell adhesion molecule 1,VCAM-1 ELISA kit

  • 中文名称：
    小鼠血管内皮细胞粘附分子1(VCAM-1/CD106)酶联免疫试剂盒
  • 货号：
    CSB-E04754m
  • 规格：
    96T/48T
  • 价格：
    ￥3800/￥2500
  • 其他：

产品详情

  • 产品描述：
        VCAM-1（Vascular cell adhesion molecule-1），是一种膜蛋白，广泛分布于内皮细胞、平滑肌细胞和其他细胞表面。VCAM-1在白细胞黏附、炎症、肿瘤转移、心血管疾病等过程中发挥重要作用。炎症和某些疾病状态下，细胞会产生和释放更多的VCAM-1。VCAM-1的含量变化可以作为许多疾病的标志物，如动脉粥样硬化、类风湿性关节炎、溃疡性结肠炎等。因此，VCAM-1是研究和治疗炎症和慢性疾病的重要目标。
        j9九游会登录入口首页生物所提供的Mouse Vascular cell adhesion molecule 1,VCAM-1 ELISA kit属于ELISA检测试剂盒，采用双抗夹心法定量检测鼠血清、血浆、细胞培养上清、组织匀浆样本中的VCAM1，其灵敏度为29.649 pg/mL，检测范围为39.062 pg/mL-2500 pg/mL。
     
  • 别名：
    Vcam1; Vcam-1; Vascular cell adhesion protein 1; V-CAM 1; VCAM-1; CD antigen CD106
  • 缩写：
  • Uniprot No.：
  • 种属：
    Mus musculus (Mouse)
  • 样本类型：
    serum, plasma, cell culture supernates, tissue homogenates
  • 检测范围：
    39.062 pg/mL-2500 pg/mL
  • 灵敏度：
    29.649 pg/mL
  • 反应时间：
    1-5h
  • 样本体积：
    50-100ul
  • 检测波长：
    450 nm
  • 研究领域：
    Cardiovascular
  • 测定原理：
    quantitative
  • 测定方法：
    Sandwich
  • 精密度：

     

    Intra-assay Precision (Precision within an assay): CV%<8%

    Three samples of known concentration were tested twenty times on one plate to assess.

    Inter-assay Precision (Precision between assays): CV%<10%

    Three samples of known concentration were tested in twenty assays to assess.

     

  • 线性度：

     

    To assess the linearity of the assay, samples were spiked with high concentrations of mouse VCAM-1/CD106 in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.

     

  • 标准曲线：

     

    These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

     

  • 数据处理：
  • 货期：
    3-5 working days

产品评价

靶点详情

  • 最新研究进展：
    VCAM1是一种黏附分子，参与细胞黏附和迁移过程，已被证实与许多疾病的发生和发展有关，如动脉粥样硬化和肿瘤的形成。最新的研究表明，VCAM1可能参与心血管疾病的发生和发展，并被认为是一种治疗心血管疾病的潜在靶点。此外，VCAM1的水平还可以作为某些疾病的诊断和预后标志物。
  • 功能：
    Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation.
  • 亚细胞定位：
    [Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Cell membrane; Lipid-anchor, GPI-anchor.
  • 组织特异性：
    Expressed on inflamed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflamed tissue. Expressed in the bone marrow.
  • 数据库链接：