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  4. Mouse Complement C1q tumor necrosis factor-related protein 6(C1QTNF6) ELISA kit

Mouse Complement C1q tumor necrosis factor-related protein 6(C1QTNF6) ELISA kit

  • 中文名称：
    小鼠补体C1q肿瘤坏死因子相关蛋白6(C1QTNF6)酶联免疫试剂盒
  • 货号：
    CSB-EL003651MO
  • 规格：
    96T/48T
  • 价格：
    ￥3600/￥2500
  • 其他：

产品详情

  • 别名：
    C1qtnf6Complement C1q tumor necrosis factor-related protein 6 ELISA Kit
  • 缩写：
    C1QTNF6
  • Uniprot No.：
  • 种属：
    Mus musculus (Mouse)
  • 检测范围：
    Request Information
  • 灵敏度：
    Request Information
  • 反应时间：
    1-5h
  • 样本体积：
    50-100ul
  • 检测波长：
    450 nm
  • 研究领域：
    Others
  • 货期：
    3-5 working days

产品评价

靶点详情

  • 基因功能参考文献：
    1. The results establish CTRP6 as a novel metabolic/immune regulator linking obesity to adipose tissue inflammation and insulin resistance. PMID: 28726640
    2. CTRP6 knockdown down-regulated the levels of lipogenic genes and phosphorylated Erk1/2 (p-Erk1/2) in the early lipogenic stage, whereas up-regulated p-Erk1/2 in the terminal differentiation in skeletal myoblasts. PMID: 27125977
    3. CTRP6 specifically suppresses the alternative pathway of the complement system. C1qtnf6(-/-) mice are highly susceptible to induced arthritis, Arthus reaction, and experimental autoimmune encephalomyelitis. PMID: 26404464
    4. Knockdown of CTRP6 can inhibit adipogenesis of 3T3-L1 adipocytes through lipogenic marker genes and Erk1/2 signaling pathway. PMID: 25639984
    5. CTRP6 plays a role in fatty acid metabolism via the AMPK-ACC pathway. The globular domain of CTRP6 mediates the phosphorylation and activation of the 5'-AMP-activated protein kinase (AMPK) in skeletal muscle cells. PMID: 20102710

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  • 亚细胞定位：
    Secreted.
  • 数据库链接：