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  4. Mouse Carbonic anhydrase 3(CA3) ELISA kit

Mouse Carbonic anhydrase 3(CA3) ELISA kit

  • 中文名称：
    小鼠碳酸酐酶3(CA3)酶联免疫试剂盒
  • 货号：
    CSB-EL004371MO
  • 规格：
    96T/48T
  • 价格：
    ￥3600/￥2500
  • 其他：

产品详情

  • 产品描述：

    This Mouse CA3 ELISA Kit was designed for the quantitative measurement of Mouse CA3 protein in serum, plasma, tissue homogenates. It is a Sandwich ELISA kit, its detection range is 4.69 pg/mL-300 pg/mL and the sensitivity is 1.17 ng/mL.

  • 别名：
    Ca3 ELISA Kit; Car3Carbonic anhydrase 3 ELISA Kit; EC 4.2.1.1 ELISA Kit; Carbonate dehydratase III ELISA Kit; Carbonic anhydrase III ELISA Kit; CA-III ELISA Kit
  • 缩写：
    CA3
  • Uniprot No.：
  • 种属：
    Mus musculus (Mouse)
  • 样本类型：
    serum, plasma, tissue homogenates
  • 检测范围：
    4.69 pg/mL-300 pg/mL
  • 灵敏度：
    1.17 ng/mL
  • 反应时间：
    1-5h
  • 样本体积：
    50-100ul
  • 检测波长：
    450 nm
  • 研究领域：
    Cell Biology
  • 测定原理：
    quantitative
  • 测定方法：
    Sandwich
  • 数据处理：
  • 货期：
    3-5 working days

产品评价

靶点详情

  • 功能：
    Reversible hydration of carbon dioxide.
  • 基因功能参考文献：
    1. CAIII is highly expressed in osteocytes, is regulated by parathyroid hormone both in vitro and in vivo, and protects osteocytes from oxidative stress. PMID: 28928248
    2. Our results indicate that Car3 is not required for de novo lipogenesis, and Car3 knockout mice fed high-fat diet do not have significant differences in responses to various diets to wild type mice. PMID: 28437447
    3. The results suggest that elevated isoaspartate and CPS-1, and reduced CA-III levels could serve as biomarkers of hepatocellular injury. PMID: 25684186
    4. We conclude that down-regulation of CAIII in preadipocytes enhances adipogenesis and that CAIII is a regulator of adipogenic differentiation which acts at the level of PPAR-gamma2 gene expression. PMID: 22507175
    5. Mice lacking carbonic anhydrase III were viable and fertile and had normal life spans. PMID: 15509796
    6. lack of proximal tubule cLCN5 in mice and men is associated with CAIII induction, increased cell proliferation, and oxidative stress PMID: 18322545

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  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    Alpha-carbonic anhydrase family
  • 组织特异性：
    Expressed at lower levels in adipose tissue from animals that were either genetically obese or had experimentally induced obesity.
  • 数据库链接：

    KEGG: mmu:12350

    STRING: 10090.ENSMUSP00000029076

    UniGene: Mm.300