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  4. Human Tryptase beta-2(TPSB2) ELISA kit

Human Tryptase beta-2(TPSB2) ELISA kit

  • 中文名称：
    人胰蛋白酶β-2(TPSB2)酶联免疫试剂盒
  • 货号：
    CSB-EL024128HU
  • 规格：
    96T/48T
  • 价格：
    ￥3600/￥2500
  • 其他：

产品详情

  • 别名：
    Mast cell tryptase beta II ELISA Kit; Mast cell tryptase beta III ELISA Kit; TPS2 ELISA Kit; TPSB2 ELISA Kit; TRYB2_HUMAN ELISA Kit; Tryptase beta 2 (gene/pseudogene) ELISA Kit; Tryptase beta-2 ELISA Kit; Tryptase II ELISA Kit; Tryptase-2 ELISA Kit; TryptaseB ELISA Kit; TryptaseC ELISA Kit
  • 缩写：
    TPSB2
  • Uniprot No.：
  • 种属：
    Homo sapiens (Human)
  • 样本类型：
    serum, plasma, tissue homogenates
  • 检测范围：
    0.137 ng/ml - 100 ng/ml
  • 灵敏度：
    0.137 ng/ml
  • 反应时间：
    1-5h
  • 样本体积：
    50-100ul
  • 检测波长：
    450 nm
  • 研究领域：
    Cell Biology
  • 测定原理：
    quantitative
  • 测定方法：
    Sandwich
  • 数据处理：
  • 货期：
    3-5 working days

产品评价

靶点详情

  • 功能：
    Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity.
  • 基因功能参考文献：
    1. These observations indicate that betaII-tryptase activity is post-translationally regulated by an allosteric disulfide bond. PMID: 24142694
    2. Results indicate a key role for heparin in the activation of human betaI- and beta2-tryptase. PMID: 15567416
    3. The disease severity and plasma tryptase levels were not affected by the number of alpha or beta tryptase alleles in mastocytosis patients. PMID: 17449330
    4. Strong linkage of TPSAB1 and TPSB2 and pairing of deficiency alleles with functional alleles in observed haplotypes protect human subjects from "knockout" genomes and indeed from inheritance of fewer than 2 active alleles. PMID: 19748655
  • 亚细胞定位：
    Secreted. Note=Released from the secretory granules upon mast cell activation.
  • 蛋白家族：
    Peptidase S1 family, Tryptase subfamily
  • 数据库链接：

    HGNC: 14120

    OMIM: 191081

    KEGG: hsa:64499

    UniGene: Hs.405479