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  4. Human Group IIF secretory phospholipase A2(PLA2G2F) ELISA kit

Human Group IIF secretory phospholipase A2(PLA2G2F) ELISA kit

  • 中文名称：
    人IIF组分泌型磷脂酶A2(PLA2G2F)酶联免疫试剂盒
  • 货号：
    CSB-EL018095HU
  • 规格：
    96T/48T
  • 价格：
    ￥3600/￥2500
  • 其他：

产品详情

  • 产品描述：

    This Human PLA2G2F ELISA Kit was designed for the quantitative measurement of Human PLA2G2F protein in serum, plasma, tissue,homogenates. It is a Sandwich ELISA kit, its detection range is 0.312 ng/mL-20 ng/mL and the sensitivity is 0.078 ng/mL.

  • 别名：
    PLA2G2FGroup IIF secretory phospholipase A2 ELISA Kit; GIIF sPLA2 ELISA Kit; sPLA2-IIF ELISA Kit; EC 3.1.1.4 ELISA Kit; Phosphatidylcholine 2-acylhydrolase 2F ELISA Kit
  • 缩写：
  • Uniprot No.：
  • 种属：
    Homo sapiens (Human)
  • 样本类型：
    serum, plasma, tissue,homogenates
  • 检测范围：
    0.312 ng/mL-20 ng/mL
  • 灵敏度：
    0.078 ng/mL
  • 反应时间：
    1-5h
  • 样本体积：
    50-100ul
  • 检测波长：
    450 nm
  • 研究领域：
    Metabolism
  • 测定原理：
    quantitative
  • 测定方法：
    Sandwich
  • 数据处理：
  • 货期：
    3-5 working days

产品评价

靶点详情

  • 功能：
    Secretory calcium-dependent phospholipase A2 that primarily targets extracellular phospholipids. Hydrolyzes the ester bond of the fatty acyl group attached at the sn-2 position of phospholipids (phospholipase A2 activity), the catalytic efficiency decreasing in the following order: phosphatidylglycerols > phosphatidylethanolamines > phosphatidylcholines > phosphatidylserines. May play a role in lipid mediator production in inflammatory conditions, by providing arachidonic acid to downstream cyclooxygenases and lipoxygenases.
  • 基因功能参考文献：
    1. two of these isoforms, sPLA2 IIA and sPLA2 IIF, localize to the upper stratum granulosum and increase in response to experimental barrier perturbation. PMID: 24269828
  • 亚细胞定位：
    [Isoform 1]: Secreted. Cell membrane; Peripheral membrane protein.
  • 蛋白家族：
    Phospholipase A2 family
  • 组织特异性：
    Expressed at high levels in placenta, testis, thymus and at lower levels in heart, kidney, liver and prostate. Highly expressed in rheumatoid arthritic tissues, including synovial lining cells in the intima, capillary endothelial cells and plasma cells.
  • 数据库链接：

    HGNC: 30040

    KEGG: hsa:64600

    STRING: 9606.ENSP00000364243

    UniGene: Hs.302034