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  4. Human Complement C1q-like protein 3(C1QL3) ELISA kit

Human Complement C1q-like protein 3(C1QL3) ELISA kit

  • 中文名称：
    人补体C1q样蛋白3(C1QL3)酶联免疫试剂盒
  • 货号：
    CSB-EL003644HU
  • 规格：
    96T/48T
  • 价格：
    ￥3600/￥2500
  • 其他：

产品详情

  • 产品描述：

    This Human C1QL3 ELISA Kit was designed for the quantitative measurement of Human C1QL3 protein in serum, plasma, tissue homogenates. It is a Sandwich ELISA kit, its detection range is 0.312 ng/mL-20 ng/mL and the sensitivity is 0.078 ng/mL.

  • 别名：
    C1q and tumor necrosis factor-related protein 13 ELISA Kit; C1q/TNF-related protein 13 ELISA Kit; C1ql ELISA Kit; C1QL3 ELISA Kit; C1QL3_HUMAN ELISA Kit; C1QTNF13 ELISA Kit; Complement C1q-like protein 3 ELISA Kit; Complement component 1; q subcomponent-like 3 ELISA Kit; CTRP13 ELISA Kit; K100 ELISA Kit
  • 缩写：
    C1QL3
  • Uniprot No.：
  • 种属：
    Homo sapiens (Human)
  • 样本类型：
    serum, plasma, tissue homogenates
  • 检测范围：
    0.312 ng/mL-20 ng/mL
  • 灵敏度：
    0.078 ng/mL
  • 反应时间：
    1-5h
  • 样本体积：
    50-100ul
  • 检测波长：
    450 nm
  • 研究领域：
    Others
  • 测定原理：
    quantitative
  • 测定方法：
    Sandwich
  • 精密度：
    Intra-assay Precision (Precision within an assay): CV%<8%      
    Three samples of known concentration were tested twenty times on one plate to assess.  
    Inter-assay Precision (Precision between assays): CV%<10%      
    Three samples of known concentration were tested in twenty assays to assess.    
                 
  • 线性度：
    To assess the linearity of the assay, samples were spiked with high concentrations of human C1QL3 in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
      Sample Serum(n=4)  
    1:1 Average % 105  
    Range % 100-110  
    1:2 Average % 99  
    Range % 95-107  
    1:4 Average % 89  
    Range % 85-93  
    1:8 Average % 84  
    Range % 80-88  
  • 回收率：
    The recovery of human C1QL3 spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.
    Sample Type Average % Recovery Range  
    Serum (n=5) 95 90-100  
    EDTA plasma (n=4) 90 85-95  
                 
                 
  • 标准曲线：
    These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
    ng/ml OD1 OD2 Average Corrected  
    20 2.510 2.350 2.430 2.292  
    10 1.961 1.856 1.909 1.771  
    5 1.276 1.324 1.300 1.162  
    2.5 0.799 0.825 0.812 0.674  
    1.25 0.453 0.427 0.440 0.302  
    0.625 0.347 0.372 0.360 0.222  
    0.312 0.262 0.259 0.261 0.123  
    0 0.141 0.135 0.138    
  • 数据处理：
  • 货期：
    3-5 working days

产品评价

靶点详情

  • 功能：
    May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses. Plays a role in glucose homeostasis. Via AMPK signaling pathway, stimulates glucose uptake in adipocytes, myotubes and hepatocytes and enhances insulin-stimulated glucose uptake. In a hepatoma cell line, reduces the expression of gluconeogenic enzymes G6PC1 and PCK1 and hence decreases de novo glucose production.
  • 基因功能参考文献：
    1. CTRP13 is a novel adipokine that is down-regulated in the serum of type 2 diabetics. PMID: 28182339
    2. decreased levels of CTRP3 and especially CTRP13 were associated with increased risk of T2DM and CAD PMID: 28033351
    3. CTRP13 reduces glucose output in hepatocytes by inhibiting the mRNA expression of gluconeogenic enzymes, glucose-6-phosphatase and the cytosolic form of phosphoenolpyruvate carboxykinase. PMID: 21378161
  • 亚细胞定位：
    Secreted.
  • 组织特异性：
    Highly expressed in adipose tissue, with expression levels at least 2 orders of magnitude higher than in other tissues, including brain and kidney.
  • 数据库链接：

    HGNC: 19359

    OMIM: 615227

    KEGG: hsa:389941

    UniGene: Hs.676792