Ripk2
RIPK2，即受体相互作用蛋白激酶2，别名Receptor-Interacting Serine/Threonine-Protein Kinase 2、CARD-Containing IL-1 Beta ICE-Kinase、Receptor-Interacting Protein 2、Tyrosine-Protein Kinase RIPK2等。它是一种在人体组织中广泛表达的双特异性激酶，主要分布在细胞质中，其mRNA水平在脾脏、白细胞、胎盘、睾丸和心脏中高表达 。RIPK2的作用机制涉及与肿瘤坏死因子受体（TNFR）的相互作用，并参与Toll样受体（TLR）和核苷酸结合寡聚化结构域（NOD）信号通路。它在细胞凋亡、细胞程序性坏死以及炎症信号通路中发挥关键作用，是先天免疫、适应性免疫和细胞凋亡的重要接头分子。RIPK2的功能异常与多种疾病有关，包括炎症性疾病、自身免疫性疾病和肿瘤 。RIPK2在生物学上的意义非常广泛，它不仅参与了细胞的生存、死亡和炎症反应的调控，还与疾病的治疗提供了新的思路。RIPK2的抑制剂在炎症反应、自身免疫性疾病和肿瘤中具有重要意义，并且在药理学上被认为是一种有前途的治疗策略 。
热销产品
Recombinant Human Receptor-interacting serine/threonine-protein kinase 2 (RIPK2) (CSB-EP019736HU)
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
RIPK2 Antibody (CSB-PA019736ESR1HU)
验证数据
Immunohistochemistry of paraffin-embedded human prostate tissue using CSB-PA019736ESR1HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA019736ESR1HU at dilution of 1:100
Ripk2 Antibodies
Ripk2 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA019736GA01HU | RIPK2 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA019736LD01HU | RIPK2 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA019736LC01HU | RIPK2 Antibody, FITC conjugated | Human | |
| CSB-PA019736LA01HU | RIPK2 Antibody | Human, Rat | ELISA, WB, IHC, IF |
| CSB-PA231579 | Phospho-RIPK2 (Ser176) Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA070142 | Phospho-RIPK2 (S176) Antibody | Human,Mouse | WB, IHC, ELISA |
| CSB-PA070143 | RIPK2 Antibody | Human,Mouse | WB, IHC, ELISA |
| CSB-PA019736ESR1HU | RIPK2 Antibody | Human | ELISA, IHC |
Ripk2 Proteins
Ripk2 Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP019736MO CSB-EP019736MO CSB-BP019736MO CSB-MP019736MO CSB-EP019736MO-B |
Recombinant Mouse Receptor-interacting serine/threonine-protein kinase 2 (Ripk2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Ripk2 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP019736HU CSB-BP019736HU CSB-MP019736HU CSB-EP019736HU-B |
Recombinant Human Receptor-interacting serine/threonine-protein kinase 2 (RIPK2) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP019736HU | Recombinant Human Receptor-interacting serine/threonine-protein kinase 2 (RIPK2) | E.coli |
| CSB-EP019736HUc7 | Recombinant Human Receptor-interacting serine/threonine-protein kinase 2 (RIPK2) | E.coli |
| CSB-EP019736HUe0 | Recombinant Human Receptor-interacting serine/threonine-protein kinase 2 (RIPK2) | E.coli |
Ripk2 Proteins for Bos taurus (Bovine)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP666184BO CSB-EP666184BO CSB-BP666184BO CSB-MP666184BO CSB-EP666184BO-B |
Recombinant Bovine Receptor-interacting serine/threonine-protein kinase 2 (RIPK2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
