Mmp9
MMP9，即基质金属蛋白酶9。它是一种在多种细胞类型中表达的酶，包括中性粒细胞、单核细胞、巨噬细胞等。MMP9的来源是人体细胞自身的基因编码，其作用机制涉及催化细胞外基质(extracellular matrix, ECM)成分的降解，如胶原蛋白、弹性蛋白、明胶等，对维持组织结构和功能的动态平衡至关重要。MMP9的活性受到多种调控机制的影响，包括酶原激活、抑制因子如金属蛋白酶组织抑制因子(TIMPs)的抑制作用 。MMP9在生物学上的意义非常广泛，它参与了多种生理和病理过程，包括组织修复、炎症反应、肿瘤发展和转移等。MMP9通过降解ECM和非ECM底物，如细胞因子和生长因子，参与调节细胞增殖、迁移和凋亡等过程。在疾病状态下，MMP9的异常表达或活性与心血管疾病、纤维化疾病、肿瘤侵袭和转移等有关。例如，在心肌梗塞后的心脏重构中，MMP9的活性增加与心脏功能障碍相关 。MMP9的活性还与肿瘤微环境中的血管生成和免疫逃逸有关，使其成为癌症治疗的潜在靶点 。
热销产品
Recombinant Horse Matrix metalloproteinase-9 (MMP9), partial (CSB-YP3996HO)
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
验证数据
Western blot analysis of extracts from Hela cells using MMP-9 Antibody.
Mmp9 Antibodies
Mmp9 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA014679GA01HU | MMP9 Antibody | human | ELISA,WB,IHC |
| CSB-PA436677 | MMP9 Antibody | Human | ELISA,WB,IHC |
| CSB-PA142806 | MMP9 Antibody | Human | ELISA,WB,IHC |
| CSB-PA002676 | MMP9 Antibody | Human | WB, IHC, IF, ELISA |
| CSB-PA005569 | MMP9 Antibody | Human | WB, ELISA |
| CSB-PA699938 | MMP9 Antibody | Human | ELISA,IHC |
| CSB-PA255651 | MMP9 Antibody | Human | ELISA,IHC |
| CSB-PA563134 | MMP9 Antibody | Human | ELISA,IHC |
| CSB-PA151401 | MMP9 Antibody | Human | ELISA,WB,IHC |
| CSB-PA294107 | MMP9 Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA796774 | MMP9 Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-RA014679A0HU | MMP9 Recombinant Monoclonal Antibody | Human | ELISA, IHC, FC |
Mmp9 Proteins
Mmp9 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP014679HU | Recombinant Human Matrix metalloproteinase-9 (MMP9), partial | Yeast |
| CSB-EP014679HU CSB-BP014679HU CSB-MP014679HU CSB-EP014679HU-B |
Recombinant Human Matrix metalloproteinase-9 (MMP9), partial | E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Mmp9 Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP014679MO CSB-EP014679MO CSB-BP014679MO CSB-MP014679MO CSB-EP014679MO-B |
Recombinant Mouse Matrix metalloproteinase-9 (Mmp9) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Mmp9 Proteins for Oryctolagus cuniculus (Rabbit)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP014679RB CSB-EP014679RB CSB-BP014679RB CSB-MP014679RB CSB-EP014679RB-B |
Recombinant Rabbit Matrix metalloproteinase-9 (MMP9), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Mmp9 Proteins for Bos taurus (Bovine)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-EP014679BO CSB-BP014679BO CSB-MP014679BO CSB-EP014679BO-B |
Recombinant Bovine Matrix metalloproteinase-9 (MMP9) | E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Mmp9 Proteins for Canis lupus familiaris (Dog) (Canis familiaris)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP014679DO | Recombinant Dog Matrix metalloproteinase-9 (MMP9) | Yeast |
Mmp9 Proteins for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP014679RA CSB-EP014679RA CSB-BP014679RA CSB-MP014679RA CSB-EP014679RA-B |
Recombinant Rat Matrix metalloproteinase-9 (Mmp9) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Mmp9 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-EP014679DO CSB-BP014679DO CSB-MP014679DO CSB-EP014679DO-B |
Recombinant Dog Matrix metalloproteinase-9 (MMP9) | E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Mmp9 ELISA Kit
Mmp9 ELISA Kit for Canis lupus familiaris (Dog) (Canis familiaris)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E13887c | Dog matrix metalloproteinase 9/Gelatinase B,MMP-9 ELISA Kit | serum, plasma | 3.12 ng/mL |
Mmp9 ELISA Kit for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E08007m | Mouse matrix metalloproteinase 9/Gelatinase B,MMP-9 ELISA Kit | serum, plasma, tissue homogenates | 0.552 ng/mL |
Mmp9 ELISA Kit for Oryctolagus cuniculus (Rabbit)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E06933Rb | Rabbit matrix metalloproteinase 9,MMP-9 ELISA Kit | serum, plasma, cell culture supernates, tissue homogenates | 5.8 pg/mL |
Mmp9 ELISA Kit for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E08008r | Rat matrix metalloproteinase 9/Gelatinase B,MMP-9 ELISA Kit | serum, plasma, tissue homogenates. | 0.195 ng/ml. |
Mmp9 ELISA Kit for Homo sapiens (Human)
| 产品货号 | 产品名称 | 样本类型 | 灵敏度 |
|---|---|---|---|
| CSB-E08006h | Human matrix metalloproteinase 9/Gelatinase B,MMP-9 ELISA Kit | serum, plasma, tissue homogenates, cell culture supernates, urine | 0.284 ng/mL |
