Il24
IL24,即白细胞介素24,它是一种由T细胞、B细胞、巨噬细胞和树突状细胞等多种免疫细胞产生的细胞因子。IL24属于IL-10细胞因子家族,通过与特异性受体复合体结合,如IL20RA/IL20RB或IL20RB/IL22RA1,激活下游的JAK-STAT信号通路,进而调控免疫反应和细胞增殖。其作用机制包括促进肿瘤细胞凋亡、抑制肿瘤血管生成,以及增强对放化疗的敏感性。在生物学意义上,IL24具有抗肿瘤活性,其表达水平与多种肿瘤的低恶性和转移性相关,是肿瘤治疗和免疫调节的潜在靶点。
热销产品
IL24 Antibody (CSB-PA613378LA01HU)
验证数据
IHC image of CSB-PA613378LA01HU diluted at 1:1400 and staining in paraffin-embedded human prostate cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
IHC image of CSB-PA613378LA01HU diluted at 1:1400 and staining in paraffin-embedded human melanoma performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Il24 Antibodies
Il24 for Homo sapiens (Human)
产品货号 | 产品名称 | 种属反应性 | 应用类型 |
---|---|---|---|
CSB-PA011640GA01HU | IL24 Antibody | Human,Mouse | ELISA,WB |
CSB-PA005671 | IL24 Antibody | Human | WB, ELISA |
CSB-PA613378LA01HU | IL24 Antibody | Human | ELISA, IHC |
CSB-PA613378LB01HU | IL24 Antibody, HRP conjugated | Human | ELISA |
CSB-PA613378LC01HU | IL24 Antibody, FITC conjugated | Human | |
CSB-PA613378LD01HU | IL24 Antibody, Biotin conjugated | Human | ELISA |
Il24 Proteins
Il24 Proteins for Homo sapiens (Human)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP613378HU CSB-EP613378HU CSB-BP613378HU CSB-MP613378HU CSB-EP613378HU-B |
Recombinant Human Interleukin-24 (IL24) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il24 Proteins for Mus musculus (Mouse)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP821683MO CSB-EP821683MO CSB-BP821683MO CSB-MP821683MO CSB-EP821683MO-B |
Recombinant Mouse Interleukin-24 (Il24) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il24 Proteins for Rattus norvegicus (Rat)
产品货号 | 产品名称 | 来源 |
---|---|---|
CSB-YP881300RA CSB-EP881300RA CSB-BP881300RA CSB-MP881300RA CSB-EP881300RA-B |
Recombinant Rat Interleukin-24 (Il24) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Il24 ELISA Kit
Il24 ELISA Kit for Homo sapiens (Human)
产品货号 | 产品名称 | 样本类型 | 灵敏度 |
---|---|---|---|
CSB-E15840h | Human Interleukin 24(IL-24)ELISA Kit | serum, plasma, tissue homogenates | 0.078 ng/ml |