Il23a

IL23A，即白细胞介素23α，是位于12号染色体上的一个基因。该基因编码的蛋白质是白细胞介素23（IL-23）的一个亚单位，与IL12B基因编码的p40亚基结合，形成具有生物学活性的IL-23异二聚体。IL-23通过与其特异性受体IL23R结合，激活下游信号传导，主要通过JAK-STAT途径，特别是STAT3和STAT4的激活，促进Th17细胞的分化和增殖，以及细胞因子如IL-17和IL-22的产生。IL23A在调节免疫反应中起着关键作用，特别是在促进Th17细胞介导的免疫反应中。Th17细胞与多种炎症性和自身免疫性疾病的发生发展密切相关，如炎症性肠病、银屑病和多发性硬化症等。此外，IL-23在肿瘤免疫中也发挥作用，影响肿瘤的生长和免疫抑制环境。因此，IL23A是免疫调节和相关疾病治疗研究中的一个重要分子。

热销产品

Recombinant Guinea pig Interleukin-23 subunit alpha (IL23A) (CSB-EP757211GU)

验证数据

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

IL23A Recombinant Monoclonal Antibody (CSB-RA251959A0HU)

验证数据

Western Blot
Positive WB detected in: THP-1 whole cell lysate
All lanes: IL23 antibody at 1:1000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 21 kDa
Observed band size: 21 kDa

Human Interleukin-23 subunit alpha(IL-23A) Elisa kit (CSB-E17339h)

验证数据

货号：CSB-E17339h

规格：96T/48T

灵敏度：15.6 pg/mL

检测范围：62.5 pg/mL-4000 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Il23a Antibody

Il23a Protein

Il23a ELISA Kit

Il23a Antibodies

Il23a for Homo sapiens (Human)

产品货号	产品名称	种属反应性	应用类型
CSB-PA06719A0Rb	IL23A Antibody	Human	ELISA, IHC, IF
CSB-PA06719B0Rb	IL23A Antibody, HRP conjugated	Human	ELISA
CSB-PA06719C0Rb	IL23A Antibody, FITC conjugated	Human
CSB-PA06719D0Rb	IL23A Antibody, Biotin conjugated	Human	ELISA
CSB-RA251959A0HU	IL23A Recombinant Monoclonal Antibody	Human	ELISA, WB

Il23a Proteins

Il23a Proteins for Equus caballus (Horse)

产品货号	产品名称	来源
CSB-YP727376HO CSB-EP727376HO CSB-BP727376HO CSB-MP727376HO CSB-EP727376HO-B	Recombinant Horse Interleukin-23 subunit alpha (IL23A)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

Il23a Proteins for Cavia porcellus (Guinea pig)

产品货号	产品名称	来源
CSB-YP757211GU CSB-BP757211GU CSB-MP757211GU CSB-EP757211GU-B	Recombinant Guinea pig Interleukin-23 subunit alpha (IL23A)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP757211GU	Recombinant Guinea pig Interleukin-23 subunit alpha (IL23A)	E.coli

Il23a Proteins for Rattus norvegicus (Rat)

产品货号	产品名称	来源
CSB-YP852813RA CSB-EP852813RA CSB-BP852813RA CSB-MP852813RA CSB-EP852813RA-B	Recombinant Rat Interleukin-23 subunit alpha (Il23a)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

Il23a Proteins for Mus musculus (Mouse)

产品货号	产品名称	来源
CSB-YP863641MO CSB-BP863641MO CSB-EP863641MO-B	Recombinant Mouse Interleukin-23 subunit alpha (Il23a)	Yeast Baculovirus In Vivo Biotinylation in E.coli
CSB-EP863641MO	Recombinant Mouse Interleukin-23 subunit alpha (Il23a), partial	E.coli
CSB-CF863641MO	Recombinant Mouse Interleukin-23 subunit alpha (Il23a)	in vitro E.coli expression system

Il23a Proteins for Homo sapiens (Human)

产品货号	产品名称	来源
CSB-YP868278HU CSB-EP868278HU CSB-BP868278HU CSB-MP868278HU CSB-EP868278HU-B	Recombinant Human Interleukin-23 subunit alpha (IL23A)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-AP004661HU	Recombinant Human IL23A & IL12B Heterodimer Protein (Active)	Mammalian cell

Il23a Proteins for Sus scrofa (Pig)

产品货号	产品名称	来源
CSB-YP873568PI CSB-BP873568PI CSB-EP873568PI-B	Recombinant Pig Interleukin-23 subunit alpha (IL23A)	Yeast Baculovirus In Vivo Biotinylation in E.coli
CSB-CF873568PI	Recombinant Pig Interleukin-23 subunit alpha (IL23A)	in vitro E.coli expression system