Drd1
DRD1，即多巴胺受体D1，别名D(1A dopamine receptor、Dopamine D1 receptor。它是一种G蛋白偶联受体，属于多巴胺受体家族中的一员，由人体细胞自身的DRD1基因编码。DRD1在大脑中的多个区域表达，包括前额叶皮层、纹状体、海马体等，参与调节多种生理功能。DRD1的作用机制主要是通过与多巴胺结合，激活G蛋白，进而影响细胞内的信号传递。DRD1主要通过Gαs蛋白激活腺苷酸环化酶，增加cAMP的产生，从而调节蛋白激酶A（PKA）的活性，影响细胞的生理反应。DRD1参与调节认知功能、运动控制、情绪反应等多种生理过程。DRD1的功能异常与多种神经系统疾病有关，包括帕金森病、精神分裂症、注意力缺陷多动障碍（ADHD）等。DRD1的激活与多巴胺信号通路中的其他受体如DRD2（多巴胺受体D2）存在交互作用，共同影响行为和情绪。此外，DRD1也是药物开发的重要靶点，例如，某些抗精神病药物和治疗帕金森病的药物通过调节DRD1的活性发挥作用。因此，DRD1是神经科学和精神药理学研究中的关键分子。
热销产品
Recombinant Human D (1A) dopamine receptor (DRD1), partial (CSB-EP007178HU1)
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
DRD1 Antibody (CSB-PA007178LA01HU)
验证数据
Western Blot
Positive WB detected in: A549 whole cell lysate
All lanes: DRD1 antibody at 3.5µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 50 kDa
Observed band size: 50 kDa
Immunohistochemistry analysis of human lung cancer using CSB-PA007178LA01HU at dilution of 1:100
Immunofluorescent analysis of A549 cells using CSB-PA007178LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
Drd1 Antibodies
Drd1 for Homo sapiens (Human)
| 产品货号 | 产品名称 | 种属反应性 | 应用类型 |
|---|---|---|---|
| CSB-PA007178GA01HU | DRD1 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA007829 | DRD1 Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
| CSB-PA343762 | DRD1 Antibody | Human | ELISA,WB,IHC |
| CSB-PA572992 | DRD1 Antibody | Human | ELISA,WB |
| CSB-PA007178LA01HU | DRD1 Antibody | Human | ELISA, WB, IHC, IF |
| CSB-PA007178LB01HU | DRD1 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA007178LC01HU | DRD1 Antibody, FITC conjugated | Human | |
| CSB-PA007178LD01HU | DRD1 Antibody, Biotin conjugated | Human | ELISA |
Drd1 Proteins
Drd1 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP007178HU1 CSB-BP007178HU1 CSB-MP007178HU1 CSB-EP007178HU1-B |
Recombinant Human D (1A) dopamine receptor (DRD1), partial | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF007178HU | Recombinant Human D (1A) dopamine receptor (DRD1) | in vitro E.coli expression system |
| CSB-EP007178HU1 | Recombinant Human D (1A) dopamine receptor (DRD1), partial | E.coli |
Drd1 Proteins for Sus scrofa (Pig)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP007178PI1 CSB-EP007178PI1 CSB-BP007178PI1 CSB-MP007178PI1 CSB-EP007178PI1-B |
Recombinant Pig D (1A) dopamine receptor (DRD1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF007178PI | Recombinant Pig D (1A) dopamine receptor (DRD1) | in vitro E.coli expression system |
Drd1 Proteins for Oryctolagus cuniculus (Rabbit)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP007178RB1 CSB-EP007178RB1 CSB-BP007178RB1 CSB-MP007178RB1 CSB-EP007178RB1-B |
Recombinant Rabbit D (1A) dopamine receptor (DRD1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF007178RB | Recombinant Rabbit D (1A) dopamine receptor (DRD1) | in vitro E.coli expression system |
Drd1 Proteins for Macaca mulatta (Rhesus macaque)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP007178MOW1 CSB-EP007178MOW1 CSB-BP007178MOW1 CSB-MP007178MOW1 CSB-EP007178MOW1-B |
Recombinant Macaca mulatta (Rhesus macaque) D (1A) dopamine receptor (DRD1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF007178MOW | Recombinant Macaca mulatta (Rhesus macaque) D (1A) dopamine receptor (DRD1) | in vitro E.coli expression system |
Drd1 Proteins for Rattus norvegicus (Rat)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP322481RA1 CSB-EP322481RA1 CSB-BP322481RA1 CSB-MP322481RA1 CSB-EP322481RA1-B |
Recombinant Rat D (1A) dopamine receptor (Drd1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF322481RA | Recombinant Rat D (1A) dopamine receptor | in vitro E.coli expression system |
Drd1 Proteins for Xenopus laevis (African clawed frog)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP331477XBE1 CSB-EP331477XBE1 CSB-BP331477XBE1 CSB-MP331477XBE1 CSB-EP331477XBE1-B |
Recombinant Xenopus laevis D (1A) dopamine receptor, partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF331477XBE | Recombinant Xenopus laevis D (1A) dopamine receptor | in vitro E.coli expression system |
Drd1 Proteins for Mus musculus (Mouse)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP713981MO CSB-EP713981MO CSB-BP713981MO CSB-MP713981MO CSB-EP713981MO-B |
Recombinant Mouse D (1A) dopamine receptor (Drd1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Drd1 Proteins for Bos taurus (Bovine)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-YP822045BO1 CSB-EP822045BO1 CSB-BP822045BO1 CSB-MP822045BO1 CSB-EP822045BO1-B |
Recombinant Bovine D (1A) dopamine receptor (DRD1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF822045BO | Recombinant Bovine D (1A) dopamine receptor (DRD1) | in vitro E.coli expression system |
