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  4. Recombinant Tetronarce californica Acetylcholine receptor subunit alpha (CHRNA1), partial

Recombinant Tetronarce californica Acetylcholine receptor subunit alpha (CHRNA1), partial

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  • 中文名称：
    Recombinant Tetronarce californica Acetylcholine receptor subunit alpha(CHRNA1),partial
  • 货号：
    CSB-EP005386TOTa2
  • 规格：
    ￥2328
  • 图片：
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
    • Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP005386TOTa2 could indicate that this peptide derived from E.coli-expressed Tetronarce californica (Pacific electric ray) (Torpedo californica) CHRNA1.
    • Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP005386TOTa2 could indicate that this peptide derived from E.coli-expressed Tetronarce californica (Pacific electric ray) (Torpedo californica) CHRNA1.
  • 其他：

产品详情

  • 纯度：
    Greater than 90% as determined by SDS-PAGE.
  • 基因名：
  • Uniprot No.：
  • 别名：
    CHRNA1Acetylcholine receptor subunit alpha
  • 种属：
    Tetronarce californica (Pacific electric ray) (Torpedo californica)
  • 蛋白长度：
    Extracellular Domain
  • 来源：
    E.coli
  • 分子量：
    40.8kDa
  • 表达区域：
    25-234aa
  • 氨基酸序列
    SEHETRLVANLLENYNKVIRPVEHHTHFVDITVGLQLIQLISVDEVNQIVETNVRLRQQWIDVRLRWNPADYGGIKKIRLPSDDVWLPDLVLYNNADGDFAIVHMTKLLLDYTGKIMWTPPAIFKSYCEIIVTHFPFDQQNCTMKLGIWTYDGTKVSISPESDRPDLSTFMESGEWVMKDYRGWKHWVYYTCCPDTPYLDITYHFIMQRI
    Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
  • 蛋白标签：
    N-terminal 6xHis-SUMO-tagged
  • 产品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 缓冲液：
    Tris-based buffer,50% glycerol
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    3-7 business days
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • 产品描述：
        Tetronarce californica Acetylcholine receptor subunit alpha (CHRNA1) 即α-神经乙酰胆碱受体（alpha-neuroacetylcholine receptor），也被简称为CHRNA11。CHRNA1是肌肉型乙酰胆碱受体的亚单位，不同于神经元型乙酰胆碱受体。CHRNA1在NSCLC中有表达，尼古丁可以激活其下游的MAPK和AKT信号通路，从而诱导药物耐药性。
        j9九游会登录入口首页生物的提供大肠杆菌表达系统表达的CHRNA1重组蛋白，表达区域为25-234aa，每个生产步骤都在严格的质量控制系统下进行，蛋白质的纯度由SDS-PAGE确定，大于90%。
  • Datasheet & COA：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
  • 亚细胞定位：
    Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Ligand-gated ion channel (TC 1.A.9) family, Acetylcholine receptor (TC 1.A.9.1) subfamily, Alpha-1/CHRNA1 sub-subfamily