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  4. Recombinant Saccharomyces cerevisiae cAMP-dependent protein kinase regulatory subunit (BCY1)

Recombinant Saccharomyces cerevisiae cAMP-dependent protein kinase regulatory subunit (BCY1)

  • 货号：
    CSB-YP357077SVG
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP357077SVG
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP357077SVG-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP357077SVG
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP357077SVG
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    BCY1
  • Uniprot No.：
  • 别名：
    BCY1; REG1; SRA1; YIL033C; cAMP-dependent protein kinase regulatory subunit; cAPK regulatory subunit; Bypass of cyclase mutations protein 1; Protein kinase A regulatory subunit; PKA regulatory subunit
  • 种属：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    2-416
  • 氨基酸序列
    VSSLPKESQ AELQLFQNEI NAANPSDFLQ FSANYFNKRL EQQRAFLKAR EPEFKAKNIV LFPEPEESFS RPQSAQSQSR SRSSVMFKSP FVNEDPHSNV FKSGFNLDPH EQDTHQQAQE EQQHTREKTS TPPLPMHFNA QRRTSVSGET LQPNNFDDWT PDHYKEKSEQ QLQRLEKSIR NNFLFNKLDS DSKRLVINCL EEKSVPKGAT IIKQGDQGDY FYVVEKGTVD FYVNDNKVNS SGPGSSFGEL ALMYNSPRAA TVVATSDCLL WALDRLTFRK ILLGSSFKKR LMYDDLLKSM PVLKSLTTYD RAKLADALDT KIYQPGETII REGDQGENFY LIEYGAVDVS KKGQGVINKL KDHDYFGEVA LLNDLPRQAT VTATKRTKVA TLGKSGFQRL LGPAVDVLKL NDPTRH
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA), an effector of the Ras/cAMP pathway. Inhibits PKA activity in the absence of cAMP. cAMP activates PKA and promotes growth and proliferation in response to good nutrient conditions. Together with ZDS1, provides a negative feedback control on the cell wall integrity-signaling pathway by acting as a negative regulator of MAP kinase SLT2/MPK1.
  • 基因功能参考文献：
    1. Data found Bcy1p a key regulator in the cAMP-PKA signalling pathway down-regulating unfolded protein response. PMID: 24722431
    2. These data indicated that Sch9 regulated localization of Bcy1 via Zds1. PMID: 22428880
    3. in addition to its negative regulatory role, the R subunit of Protein Kinase C stimulates C activity via distal interactions PMID: 18854166
  • 亚细胞定位：
    Cytoplasm. Nucleus. Note=Cytoplasmic when phosphorylated. Nuclear when not phosphorylated.
  • 蛋白家族：
    CAMP-dependent kinase regulatory chain family
  • 数据库链接：

    KEGG: sce:YIL033C

    STRING: 4932.YIL033C