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  4. Recombinant Rat Syntaxin-2 (Stx2), partial

Recombinant Rat Syntaxin-2 (Stx2), partial

  • 中文名称：
    大鼠Stx2重组蛋白
  • 货号：
    CSB-YP022898RA1
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    大鼠Stx2重组蛋白
  • 货号：
    CSB-EP022898RA1
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    大鼠Stx2重组蛋白
  • 货号：
    CSB-EP022898RA1-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    大鼠Stx2重组蛋白
  • 货号：
    CSB-BP022898RA1
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    大鼠Stx2重组蛋白
  • 货号：
    CSB-MP022898RA1
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    Stx2; Epim; Syntaxin-2; Epimorphin
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Essential for epithelial morphogenesis. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm.
  • 基因功能参考文献：
    1. miR-124a aggravates lipopolysaccharide-induced cardiac dysfunction and the miR-124a/STX2 pathway might serve as the potential diagnostic and therapeutic targets for septic cardiac dysfunction. PMID: 28560580
    2. These data provide evidence for EPIM and SOX9 functioning by mutual negative feedback to regulate attributes of the quiescent or activated state of HSCs. PMID: 24971829
    3. Epimorphin has morphogenetic effects on several epithelial tissues, including those of lung. PMID: 25119302
    4. Epimorphin regulates bile duct formation of WB-F344 cells through effects on RhoA and C/EBPbeta, implicating a dual aspect of this morphoregulator in bile duct epithelial morphogenesis. PMID: 21935930
    5. Epimorphin regulates bile duct formation via effects on mitosis orientation PMID: 20305811
    6. expression in intestinal myofibroblasts induces epithelial morphogenesis PMID: 12464668
    7. pIgA-R traffics through postendosomal rab3D-, rab11a-, and syntaxin 2-associated compartments, implicating these proteins in the regulation of transcytosis. PMID: 14578858
    8. In conclusion, epimorphin is a factor that induces differentiation of hepatic stem-like cells through epithelial-mesenchymal cell contact. PMID: 14592430
    9. anti-oxidative function of epimorphin is dramatic and is likely mediated by the activation of EGF receptors and the MEK/extracellular signal-regulated kinase and PI3 kinase/Akt signaling pathways PMID: 16891298
    10. Epimorphin elicits hepatocyte spheroids by inducing proteases in rodent hepatocytes through NF-kappaB. PMID: 17935821

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  • 亚细胞定位：
    Membrane; Single-pass type IV membrane protein.
  • 蛋白家族：
    Syntaxin family
  • 组织特异性：
    Heart, spleen, liver, and testis.
  • 数据库链接：

    KEGG: rno:25130

    STRING: 10116.ENSRNOP00000001242

    UniGene: Rn.10623