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  4. Recombinant Rat Leukotriene B4 receptor 1 (Ltb4r), partial

Recombinant Rat Leukotriene B4 receptor 1 (Ltb4r), partial

  • 中文名称：
    大鼠Ltb4r重组蛋白
  • 货号：
    CSB-YP886424RA1
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    大鼠Ltb4r重组蛋白
  • 货号：
    CSB-EP886424RA1
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    大鼠Ltb4r重组蛋白
  • 货号：
    CSB-EP886424RA1-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    大鼠Ltb4r重组蛋白
  • 货号：
    CSB-BP886424RA1
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    大鼠Ltb4r重组蛋白
  • 货号：
    CSB-MP886424RA1
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    Ltb4r; Blt; Leukotriene B4 receptor 1; LTB4-R 1; LTB4-R1
  • 种属：
    Rattus norvegicus (Rat)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response.
  • 基因功能参考文献：
    1. Study verified that both BLT1 mRNA and BLT1 protein expressions were markedly increased after subarachnoid hemorrhage and elevated BLT1 expressions were mainly found in neurons, microglia and endothelial cells rather than astrocytes. We also demonstrated that there a significant positive correlation between BLT1 and nuclear p65 protein expressions in the same specific time course. PMID: 27725151
    2. BLT1 and BLT2 were involved in synovial cell proliferation. PMID: 21189570
    3. LTB4 down-regulates airway contraction and inflammation through activation of the hypothalamic-pituitary-adrenal axis via its BLT1 receptor. PMID: 20403205
    4. The time-dependent expression of Ltb4r in experimental arthritis was studied. PMID: 17481560
    5. FcgammaRI ligation leads to a complex with BLT1 in lipid rafts that enhances rat lung macrophage antimicrobial functions. PMID: 19657115

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  • 亚细胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    G-protein coupled receptor 1 family
  • 组织特异性：
    Exclusively expressed in polymorphonuclear leukocytes.
  • 数据库链接：

    KEGG: rno:59264

    STRING: 10116.ENSRNOP00000027647

    UniGene: Rn.41003