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  4. Recombinant Pig Orexin (HCRT)

Recombinant Pig Orexin (HCRT)

  • 中文名称：
    斯克罗法HCRT重组蛋白
  • 货号：
    CSB-YP010230PI
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    斯克罗法HCRT重组蛋白
  • 货号：
    CSB-EP010230PI
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    斯克罗法HCRT重组蛋白
  • 货号：
    CSB-EP010230PI-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    斯克罗法HCRT重组蛋白
  • 货号：
    CSB-BP010230PI
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    斯克罗法HCRT重组蛋白
  • 货号：
    CSB-MP010230PI
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    HCRT
  • Uniprot No.：
  • 别名：
    HCRT; ORX; OX; PPOX; Orexin; Hypocretin; Hcrt) [Cleaved into: Orexin-A; Hypocretin-1; Hcrt1); Orexin-B; Hypocretin-2; Hcrt2)]
  • 种属：
    Sus scrofa (Pig)
  • 蛋白长度：
    Cytoplasmic domain
  • 表达区域：
    34-66
  • 氨基酸序列
    QPLPDCC RQKTCSCRLY ELLHGAGNHA AGILTL
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Orexin-A binds to both OX1R and OX2R with a high affinity, whereas orexin-B binds only to OX2R with a similar high affinity.
  • 基因功能参考文献：
    1. In summary, we revealed an important role of orexin A in the regulation of pancreatic islets biology. OxA is involved in the secretion of pancreatic hormones and prolongation of islet cell lifespan. PMID: 29550793
    2. MBH, signal intensity for OXA was highest on days 14-16. PMID: 23568972
    3. The impact of the phase of the estrous cycle on the observed changes in plasma orexin levels in domestic pigs. PMID: 23220034
    4. Prepro-orexin (PPOX) mRNA abundance was approximately 15-fold higher (P<0.05) in mandibular than in the others salivary glands. PMID: 21888930
    5. Orexin A was found in the beta cells of cattle, sheep, and swine where it may be implicated in the control of pancreatic activity. PMID: 20359730

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  • 亚细胞定位：
    Rough endoplasmic reticulum. Cytoplasmic vesicle. Cell junction, synapse.
  • 蛋白家族：
    Orexin family
  • 数据库链接：

    KEGG: ssc:397305

    STRING: 9823.ENSSSCP00000018447

    UniGene: Ssc.15983