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  4. Recombinant Mouse Aurora kinase C (Aurkc)

Recombinant Mouse Aurora kinase C (Aurkc)

  • 中文名称：
    Recombinant Mouse Aurora kinase C(Aurkc),Yeast
  • 货号：
    CSB-YP002460MO
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Mouse Aurora kinase C(Aurkc),Yeast
  • 货号：
    CSB-EP002460MO
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Mouse Aurora kinase C(Aurkc),Yeast
  • 货号：
    CSB-EP002460MO-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Mouse Aurora kinase C(Aurkc),Yeast
  • 货号：
    CSB-BP002460MO
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Mouse Aurora kinase C(Aurkc),Yeast
  • 货号：
    CSB-MP002460MO
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    Aurkc
  • Uniprot No.：
  • 别名：
    Aurkc; Aie1; Aik3; Airk3; Ark3; Stk13Aurora kinase C; EC 2.7.11.1; Aurora 3; Aurora/IPL1-related kinase 3; ARK-3; Aurora-related kinase 3; Aurora/IPL1/Eg2 protein 1; Serine/threonine-protein kinase 13; Serine/threonine-protein kinase aurora-C
  • 种属：
    Mus musculus (Mouse)
  • 蛋白长度：
    Full length protein
  • 表达区域：
    1-282
  • 氨基酸序列
    MEPSTSTRKH FTINDFEIGR PLGRGKFGRV YLARLKENHF IVALKVLFKS EIEKEGLEHQ LRREVEIQAH LQHRNILRLY NYFYDDTRIY LILEYAPGGE LYKELQRHQK LDQQRTATII QELSDALTYC HEKKVIHRDI KPENLLLGLN GEVKISDFGW SVHTPSLRRK TMCGTLDYLP PEMIAQKPYN EMVDLWCIGV LCYELLVGKP PFESSTSSET YRRIRQVDFK FPSSVPAGAQ DLISKLLRYH PSERLSLAQV LKHPWVREHS RRVLPPCVHG AS
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Plays also a role in meiosis and more particularly in spermatogenesis. Has redundant cellular functions with AURKB and can rescue an AURKB knockdown. Like AURKB, AURKC phosphorylates histone H3 at 'Ser-10' and 'Ser-28'. AURKC phosphorylates the CPC complex subunits BIRC5/survivin and INCENP leading to increased AURKC activity. Phosphorylates TACC1, another protein involved in cell division, at 'Ser-228'.
  • 亚细胞定位：
    Nucleus. Chromosome. Chromosome, centromere. Cytoplasm, cytoskeleton, spindle.
  • 蛋白家族：
    Protein kinase superfamily, Ser/Thr protein kinase family, Aurora subfamily
  • 组织特异性：
    Expressed only in testis.
  • 数据库链接：

    STRING: 10090.ENSMUSP00000083426

    UniGene: Mm.261572