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  4. Recombinant Human herpesvirus 1 Envelope glycoprotein M (gM), partial

Recombinant Human herpesvirus 1 Envelope glycoprotein M (gM), partial

  • 货号：
    CSB-YP356229HWY
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 货号：
    CSB-EP356229HWY
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 货号：
    CSB-EP356229HWY-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 货号：
    CSB-BP356229HWY
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 货号：
    CSB-MP356229HWY
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    gM
  • Uniprot No.：
  • 别名：
    gM; UL10Envelope glycoprotein M; gM
  • 种属：
    Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Envelope glycoprotein important for virion assembly and egress. Plays a role in the correct incorporation of gH-gL into virion membrane. Directs the glycoprotein N (gN) to the host trans-Golgi network.
  • 基因功能参考文献：
    1. The s propose that glycoprotein N functions in glycoprotein M-dependent as well as glycoprotein M-independent processes during which it is complemented by other viral factors. PMID: 26999189
    2. gM 19-343 was sufficient for transport to the trans-Golgi network. PMID: 26265177
    3. To better understand how HSV-1 gM localization is regulated, s evaluated its ability to bind gN and discovered it does so in both transfected and infected cells, an interaction strongly weakened by the deletion of the gM amino terminus. PMID: 25505065
    4. Viral envelope glycoprotein M (gM) as having moderate anti-tetherin activity. PMID: 24067975
    5. gM and UL11 are required for efficient membrane fusion events during virus entry and virus spread. PMID: 23678175
    6. gM becomes incorporated into the virion envelope upon budding through the INM (inner nuclear membrane). PMID: 17079321
    7. The data indicate that herpes simplex virus type 1 pUL11 and gM exhibit similar functions in cytoplasmic steps of virion assembly. PMID: 19004941
    8. nuclear gM fulfills an early nuclear function that is independent of its known interaction partners and its function in viral egress. PMID: 19812164

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  • 亚细胞定位：
    Virion membrane; Multi-pass membrane protein. Host Golgi apparatus, host trans-Golgi network. Host endosome membrane; Multi-pass membrane protein. Host nucleus inner membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Herpesviridae glycoprotein M family
  • 数据库链接：

    KEGG: vg:2703379