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  4. Recombinant Human cytomegalovirus Envelope glycoprotein US27 (US27), partial

Recombinant Human cytomegalovirus Envelope glycoprotein US27 (US27), partial

  • 中文名称：
    Recombinant Human cytomegalovirus Envelope glycoprotein US27(US27),partial,Yeast
  • 货号：
    CSB-YP518995HWW1
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Human cytomegalovirus Envelope glycoprotein US27(US27),partial,Yeast
  • 货号：
    CSB-EP518995HWW1
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Human cytomegalovirus Envelope glycoprotein US27(US27),partial,Yeast
  • 货号：
    CSB-EP518995HWW1-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Human cytomegalovirus Envelope glycoprotein US27(US27),partial,Yeast
  • 货号：
    CSB-BP518995HWW1
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Human cytomegalovirus Envelope glycoprotein US27(US27),partial,Yeast
  • 货号：
    CSB-MP518995HWW1
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    US27
  • Uniprot No.：
  • 别名：
    US27; Envelope glycoprotein US27
  • 种属：
    Human cytomegalovirus (strain Merlin) (HHV-5) (Human herpesvirus 5)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Plays an important role in spread of HCMV via the extracellular route. As a G-protein-coupled receptor (vGPCR), may activate signaling pathways important for virion assembly or egress processes.
  • 基因功能参考文献：
    1. US27 expression enhance HCMV infection by prolonging host cell survival and proliferation.[review] PMID: 28447191
    2. These results demonstrate that US27 can impact host cell physiology and may shed light on the function of this orphan viral G protein-coupled receptor. PMID: 23850869
    3. Potentiation of CXCR4 signaling by US27 could represent a novel strategy by which human cytomegalovirus targets virus-infected cells to the bone marrow in order to expand the reservoir of latently infected cells. PMID: 23490053
    4. The results indicate that the C-terminal domain of the HCMV US27 protein, which contains a di-leucine endocytic sorting motif, is both necessary and sufficient for intracellular localization. PMID: 22339884
    5. The s conclude that pUS27 acts at a late stage of the human cytomegalovirus replication cycle to support spread of virus by the extracellular route. PMID: 21307184

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  • 亚细胞定位：
    Virion. Host cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    G-protein coupled receptor 1 family
  • 数据库链接：

    KEGG: vg:3077557