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  4. Recombinant Human Serine/arginine-rich splicing factor 11 (SRSF11)

Recombinant Human Serine/arginine-rich splicing factor 11 (SRSF11)

  • 中文名称：
    人SRSF11重组蛋白
  • 货号：
    CSB-YP021144HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人SRSF11重组蛋白
  • 货号：
    CSB-EP021144HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人SRSF11重组蛋白
  • 货号：
    CSB-EP021144HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人SRSF11重组蛋白
  • 货号：
    CSB-BP021144HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人SRSF11重组蛋白
  • 货号：
    CSB-MP021144HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    SRSF11
  • Uniprot No.：
  • 别名：
    Arginine rich 54 kDa nuclear protein; Arginine-rich 54 kDa nuclear protein; arginine/serine-rich 11; dJ677H15.2; DKFZp686M13204; NET2; P54; Serine/arginine-rich splicing factor 11; SFR11; SFRS 11; Splicing factor; Splicing factor arginine/serine rich 11; Splicing factor p54; SRS11_HUMAN; SRSF11
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Full Length of Mature Protein
  • 表达区域：
    2-484
  • 氨基酸序列
    SNTTVVPST AGPGPSGGPG GGGGGGGGGG GTEVIQVTNV SPSASSEQMR TLFGFLGKID ELRLFPPDDS PLPVSSRVCF VKFHDPDSAV VAQHLTNTVF VDRALIVVPY AEGVIPDEAK ALSLLAPANA VAGLLPGGGL LPTPNPLTQI GAVPLAALGA PTLDPALAAL GLPGANLNSQ SLAADQLLKL MSTVDPKLNH VAAGLVSPSL KSDTSSKEIE EAMKRVREAQ SLISAAIEPD KKEEKRRHSR SRSRSRRRRT PSSSRHRRSR SRSRRRSHSK SRSRRRSKSP RRRRSHSRER GRRSRSTSKT RDKKKEDKEK KRSKTPPKSY STARRSRSAS RERRRRRSRS GTRSPKKPRS PKRKLSRSPS PRRHKKEKKK DKDKERSRDE RERSTSKKKK SKDKEKDRER KSESDKDVKQ VTRDYDEEEQ GYDSEKEKKE EKKPIETGSP KTKECSVEKG TGDSLRESKV NGDDHHEEDM DMSD
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May function in pre-mRNA splicing.
  • 基因功能参考文献：
    1. 1p31 SFRS11 v PMID: 24657192
    2. SRp54 interacts with a purine-rich element tau in exon 10 and antagonizes Tra2beta, an SR-domain-containing protein that enhances exon 10 inclusion. PMID: 16943417
    3. The G2/M arrest induced by MIAs is required for p54(nrb) phosphorylation. CDK activity is required for MIA-induced phosphorylation of p54(nrb). PMID: 18832053
  • 亚细胞定位：
    Nucleus. Note=Colocalizes with spliceosome components.
  • 蛋白家族：
    Splicing factor SR family
  • 数据库链接：

    HGNC: 10782

    OMIM: 602010

    KEGG: hsa:9295

    STRING: 9606.ENSP00000359988

    UniGene: Hs.479693