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  4. Recombinant Human Retinal guanylyl cyclase 2 (GUCY2F), partial

Recombinant Human Retinal guanylyl cyclase 2 (GUCY2F), partial

  • 中文名称：
    人GUCY2F重组蛋白
  • 货号：
    CSB-YP010056HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人GUCY2F重组蛋白
  • 货号：
    CSB-EP010056HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人GUCY2F重组蛋白
  • 货号：
    CSB-EP010056HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人GUCY2F重组蛋白
  • 货号：
    CSB-BP010056HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人GUCY2F重组蛋白
  • 货号：
    CSB-MP010056HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    GUCY2F
  • Uniprot No.：
  • 别名：
    GUCY2F; GUC2F; RETGC2; Retinal guanylyl cyclase 2; RETGC-2; EC 4.6.1.2; Guanylate cyclase 2F; retinal; Guanylate cyclase F; GC-F; Rod outer segment membrane guanylate cyclase 2; ROS-GC2
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Responsible for the synthesis of cyclic GMP (cGMP) in rods and cones of photoreceptors. Plays an essential role in phototransduction, by mediating cGMP replenishment. May also participate in the trafficking of membrane-asociated proteins to the photoreceptor outer segment membrane.
  • 基因功能参考文献：
    1. Results show GUCY2F gene was implicated in the pathogenesis of breast, lung, and pancreatic cancers and it may be useful targets for diagnostic and therapeutic intervention in selected patients. PMID: 16941478
    2. Mutants of GC-activating protein 2 modulated ROS-GC2 in a manner different from their action on ROS-GC1 indicating that the Ca2+ sensitivity of the Ca2+ sensor is controlled by the mode of target-sensor interaction. PMID: 17868328
  • 亚细胞定位：
    Photoreceptor outer segment membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    Adenylyl cyclase class-4/guanylyl cyclase family
  • 组织特异性：
    Retina. Localized exclusively in the outer nuclear layer and inner segments of the rod and cone photoreceptor cells.
  • 数据库链接：

    HGNC: 4691

    OMIM: 300041

    KEGG: hsa:2986

    STRING: 9606.ENSP00000218006

    UniGene: Hs.123074