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  4. Recombinant Human Nucleoside diphosphate kinase homolog 5 (NME5)

Recombinant Human Nucleoside diphosphate kinase homolog 5 (NME5)

  • 中文名称：
    人NME5重组蛋白
  • 货号：
    CSB-YP015890HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人NME5重组蛋白
  • 货号：
    CSB-EP015890HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人NME5重组蛋白
  • 货号：
    CSB-EP015890HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人NME5重组蛋白
  • 货号：
    CSB-BP015890HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人NME5重组蛋白
  • 货号：
    CSB-MP015890HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    NME5
  • Uniprot No.：
  • 别名：
    Inhibitor of p53 induced apoptosis beta; Inhibitor of p53-induced apoptosis-beta; IPIA beta; IPIA-beta; NDK-H 5; NDK5_HUMAN; NDP kinase homolog 5; NM23 H5; nm23-H5; Nm23-M5; NM23H5; NME/NM23 family member 5; NME5; Non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase); Nonmetastatic cells 5, protein expressed in; Nonmetastatic protein 23, homolog 5; Nucleoside diphosphate kinase homolog 5; Radial spoke 23 homolog; RSPH23; Testis specific nm23 homolog; Testis-specific nm23 homolog
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Full length protein
  • 表达区域：
    1-212
  • 氨基酸序列
    MEISMPPPQI YVEKTLAIIK PDIVDKEEEI QDIILRSGFT IVQRRKLRLS PEQCSNFYVE KYGKMFFPNL TAYMSSGPLV AMILARHKAI SYWLELLGPN NSLVAKETHP DSLRAIYGTD DLRNALHGSN DFAAAEREIR FMFPEVIVEP IPIGQAAKDY LNLHIMPTLL EGLTELCKQK PADPLIWLAD WLLKNNPNKP KLCHHPIVEE PY
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Does not seem to have NDK kinase activity. Confers protection from cell death by Bax and alters the cellular levels of several antioxidant enzymes including Gpx5. May play a role in spermiogenesis by increasing the ability of late-stage spermatids to eliminate reactive oxygen species.
  • 基因功能参考文献：
    1. study characterized for the first time the human NME5 promoter which is controlled by Sp1 transcription factor in pancreatic cancer PMID: 22564704
    2. found that Nm23-H5 and NDP kinases A and B are differently distributed in spermatids and mature spermatozoa and could therefore be involved at various levels of sperm differentiation and function PMID: 14499630
  • 亚细胞定位：
    Cell projection, cilium.
  • 蛋白家族：
    NDK family
  • 组织特异性：
    Specifically expressed in testis germinal cells.
  • 数据库链接：

    HGNC: 7853

    OMIM: 603575

    KEGG: hsa:8382

    STRING: 9606.ENSP00000265191

    UniGene: Hs.730856