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  4. Recombinant Human Myelin-associated oligodendrocyte basic protein (MOBP)

Recombinant Human Myelin-associated oligodendrocyte basic protein (MOBP)

  • 中文名称：
    人MOBP重组蛋白
  • 货号：
    CSB-YP014701HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人MOBP重组蛋白
  • 货号：
    CSB-EP014701HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人MOBP重组蛋白
  • 货号：
    CSB-EP014701HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人MOBP重组蛋白
  • 货号：
    CSB-BP014701HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人MOBP重组蛋白
  • 货号：
    CSB-MP014701HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    MOBP
  • Uniprot No.：
  • 别名：
    MOBP; Myelin-associated oligodendrocyte basic protein
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-183
  • 氨基酸序列
    MSQKPAKEGP RLSKNQKYSE HFSIHCCPPF TFLNSKKEIV DRKYSICKSG CFYQKKEEDW ICCACQKTRT SRRAKSPQRP KQQPAAPPAV VRAPAKPRSP PRSERQPRSP PRSERQPRSP PRSERQPRSP PRSERQPRPR PEVRPPPAKQ RPPQKSKQQP RSSPLRGPGA SRGGSPVKAS RFW
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May play a role in compacting or stabilizing the myelin sheath, possibly by binding the negatively charged acidic phospholipids of the cytoplasmic membrane.
  • 基因功能参考文献：
    1. Mutation in MOBP gene is associated with amyotrophic lateral sclerosis. PMID: 27455348
    2. rs1768208 is associated with corticobasal degeneration. PMID: 26077951
    3. The rs1768208 risk polymorphism in MOBP has prognostic value in behavioral-variant frontotemporal dementia. PMID: 24994843
    4. Genotypes at MOBP and EIF2AK3 confer risk predominantly in APOE epsilon4-positive subjects, with indications of an interaction between APOE and MOBP or EIF2AK3 on Alzheimer's disease risk. PMID: 23116876
    5. MOBP mRNA levels were increased in the DLPFC white matter in patients with a history of substance abuse. PMID: 17964117

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  • 亚细胞定位：
    Cytoplasm, perinuclear region.
  • 数据库链接：

    HGNC: 7189

    OMIM: 600948

    KEGG: hsa:4336

    UniGene: Hs.121333