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  4. Recombinant Human Mucin-like protein 1 (MUCL1)

Recombinant Human Mucin-like protein 1 (MUCL1)

  • 中文名称：
    人MUCL1重组蛋白
  • 货号：
    CSB-YP842658HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    人MUCL1重组蛋白
  • 货号：
    CSB-EP842658HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    人MUCL1重组蛋白
  • 货号：
    CSB-EP842658HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    人MUCL1重组蛋白
  • 货号：
    CSB-BP842658HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    人MUCL1重组蛋白
  • 货号：
    CSB-MP842658HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    MUCL1
  • Uniprot No.：
  • 别名：
    mucin like 1; mucin-like 1; Mucin-like protein 1; MUCL1; MUCL1_HUMAN; Protein BS106; Small breast epithelial mucin
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    full length protein
  • 表达区域：
    21-90
  • 氨基酸序列
    NPTTAAPADT YPATGPADDE APDAETTAAA TTATTAAPTT ATTAASTTAR KDIPVLPKWV GDLPNGRVCP
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    May play a role as marker for the diagnosis of metastatic breast cancer.
  • 基因功能参考文献：
    1. an important role for MUCL1 in the proliferation of breast cancer cells PMID: 26725324
    2. SBEM has the potential to be a specific marker for predicting hematogenous micrometastasis and response to neoadjuvant chemotherapy in breast cancer. PMID: 20364301
    3. identification as possible new breast tumor biomarker PMID: 15684711
    4. octamer-binding transcription factors participate in the strong expression of SBEM gene in breast tissues PMID: 16720387
    5. SBEM may identify a unique subset of breast cancers with poor prognosis and have implications for therapeutic management. PMID: 18269587
    6. results demonstrate that SBEM mRNA may be an important marker for targeting breast cancer micrometastasis PMID: 18497056
    7. The SBEM might a suitable marker for molecular detection of ITCs in BM in breast cancer patients. Analysis of prognostic value for SBEM mRNA-based assay should take into account the heterogeneity and different molecular subtypes of breast cancer. PMID: 19221791

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  • 亚细胞定位：
    Secreted. Membrane.
  • 组织特异性：
    Expressed in mammary, salivary glands and prostate. Also detected in lung. Mainly expressed in cancer cell lines of breast origin. Highly expressed in lymph node-positive compared with node-negative tumors. Detected in all lymph node containing metastatic
  • 数据库链接：

    HGNC: 30588

    OMIM: 610857

    KEGG: hsa:118430

    STRING: 9606.ENSP00000311364

    UniGene: Hs.348419