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  4. Recombinant Human Armadillo repeat-containing X-linked protein 1 (ARMCX1), partial

Recombinant Human Armadillo repeat-containing X-linked protein 1 (ARMCX1), partial

  • 中文名称：
    Recombinant Human Armadillo repeat-containing X-linked protein 1(ARMCX1),partial,Yeast
  • 货号：
    CSB-YP878960HU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    Recombinant Human Armadillo repeat-containing X-linked protein 1(ARMCX1),partial,Yeast
  • 货号：
    CSB-EP878960HU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    Recombinant Human Armadillo repeat-containing X-linked protein 1(ARMCX1),partial,Yeast
  • 货号：
    CSB-EP878960HU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    Recombinant Human Armadillo repeat-containing X-linked protein 1(ARMCX1),partial,Yeast
  • 货号：
    CSB-BP878960HU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    Recombinant Human Armadillo repeat-containing X-linked protein 1(ARMCX1),partial,Yeast
  • 货号：
    CSB-MP878960HU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    ARMCX1
  • Uniprot No.：
  • 别名：
    ARMCX 1; AD032; ALEX1; ARM protein lost in epithelial cancers on chromosome X 1; Arm protein lost in epithelial cancers X chromosome 1; Armadillo repeat containing X linked 1; Armadillo repeat containing X linked protein 1; Armadillo repeat-containing X-linked protein 1; ARMCX1; ARMX1_HUMAN; Protein ALEX1
  • 种属：
    Homo sapiens (Human)
  • 蛋白长度：
    Partial
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Regulates mitochondrial transport during axon regeneration. Increases the proportion of motile mitochondria by recruiting stationary mitochondria into the motile pool. Enhances mitochondria movement and neurite growth in both adult axons and embryonic neurons. Promotes neuronal survival and axon regeneration after nerve injury. May link mitochondria to the Trak1-kinesin motor complex via its interaction with MIRO1.
  • 基因功能参考文献：
    1. It is suggested that the ALEX1 protein is associated with tumorigenesis in cervical cancer and we speculate that the ALEX1 may plays a role as an oncogene in cervical cancer. PMID: 26464700
    2. ALEX1 is a crucial tumor suppressor gene involved in cell proliferation and apoptosis in breast cancer. PMID: 25921134
    3. Findings suggest that overexpression of ALEX1 (armadillo repeat containing, X-linked [ARMCX]) plays a negative role in colorectal tumorigenesis. PMID: 22494058
    4. Human Arm protein lost in epithelial cancers, on chromosome X 1 (ALEX1) gene is transcriptionally regulated by CREB and Wnt/beta-catenin signaling. PMID: 20398052
  • 亚细胞定位：
    Mitochondrion. Mitochondrion outer membrane; Single-pass membrane protein.
  • 蛋白家族：
    Eutherian X-chromosome-specific Armcx family
  • 组织特异性：
    Expressed at high levels ovary, heart, testis, prostate, brain, spleen and colon. Expressed at very low levels in liver and thymus. Not expressed in peripheral blood leukocytes. Not or reduced expressed in lung, prostate, colon, pancreas and ovarian carci
  • 数据库链接：

    HGNC: 18073

    OMIM: 300362

    KEGG: hsa:51309

    STRING: 9606.ENSP00000361917

    UniGene: Hs.9728