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  4. Recombinant Drosophila melanogaster Vacuolar protein-sorting-associated protein 36 (Vps36)

Recombinant Drosophila melanogaster Vacuolar protein-sorting-associated protein 36 (Vps36)

  • 中文名称：
    黑腹果蝇Vps36重组蛋白
  • 货号：
    CSB-YP892898DLU
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    黑腹果蝇Vps36重组蛋白
  • 货号：
    CSB-EP892898DLU
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    黑腹果蝇Vps36重组蛋白
  • 货号：
    CSB-EP892898DLU-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    黑腹果蝇Vps36重组蛋白
  • 货号：
    CSB-BP892898DLU
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    黑腹果蝇Vps36重组蛋白
  • 货号：
    CSB-MP892898DLU
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 别名：
    Vps36; CG10711Vacuolar protein-sorting-associated protein 36; ESCRT-II complex subunit VPS36
  • 种属：
    Drosophila melanogaster (Fruit fly)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-399
  • 氨基酸序列
    MNRFAYVEAR LSPNESFVSR DNRVKIYDGD QKTDFEDGEV VLTTHRLFWG RPGEIARAAV TLCLPLSYVI SVSEETTASN FFGRKTRIIM HLHPPTSDKG PGPLDTSRAT HIKLSGKNGL SVEFHSALRE TLNARVWEIL LTSEIIINGV ASSPTLEPAN DRLARIQKRT GIGGIERHLE AKAKATDENI ALAFQDLSVL MAMAKDMVGV SKTISSKIRK QKGEISDDET VRFKSYLMSL GIDDPVTRDN FTSNSAYFSS LARQICEMLL DPIEEQGGMM SLADVYCRVN RARGLELLSP EDLLHACEQL SGPIRLRSFP SGARVLQLES HDDALIAVDT LEKVEAAESL AVEELAKQLG ISLLLAKERL LVAERLGKVC RDESVEGLRF YPNLLLGRD
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. ESCRT-II interacts, through the Vps36 subunit, with bicoid mRNA. This interaction is required for the anterior localization of bicoid mRNA in the developing egg. Plays a role in promoting mitochondrial autophagy (mitophagy).
  • 基因功能参考文献：
    1. vps36 mutations increase apoptotic resistance, but have little effect on non-autonomous proliferation. PMID: 19132102
  • 亚细胞定位：
    Cytoplasm.
  • 蛋白家族：
    VPS36 family
  • 组织特异性：
    Ubiquitously expressed in the ovary.
  • 数据库链接：

    KEGG: dme:Dmel_CG10711

    STRING: 7227.FBpp0075560

    UniGene: Dm.7252