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  4. Recombinant Chicken Programmed cell death protein 4 (PDCD4)

Recombinant Chicken Programmed cell death protein 4 (PDCD4)

  • 中文名称：
    鸡PDCD4重组蛋白
  • 货号：
    CSB-YP857423CH
  • 规格：
  • 来源：
    Yeast
  • 其他：
  • 中文名称：
    鸡PDCD4重组蛋白
  • 货号：
    CSB-EP857423CH
  • 规格：
  • 来源：
    E.coli
  • 其他：
  • 中文名称：
    鸡PDCD4重组蛋白
  • 货号：
    CSB-EP857423CH-B
  • 规格：
  • 来源：
    E.coli
  • 共轭：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名称：
    鸡PDCD4重组蛋白
  • 货号：
    CSB-BP857423CH
  • 规格：
  • 来源：
    Baculovirus
  • 其他：
  • 中文名称：
    鸡PDCD4重组蛋白
  • 货号：
    CSB-MP857423CH
  • 规格：
  • 来源：
    Mammalian cell
  • 其他：

产品详情

  • 纯度：
    >85% (SDS-PAGE)
  • 基因名：
    PDCD4
  • Uniprot No.：
  • 别名：
    PDCD4; Programmed cell death protein 4; Protein I11/6
  • 种属：
    Gallus gallus (Chicken)
  • 蛋白长度：
    full length protein
  • 表达区域：
    1-467
  • 氨基酸序列
    MEIEKQHVYI STVEVENLSD ALFSGDEENG GSEERKTEIN GNWIPATSIT EAKINAKAKR RLRKNSSRDS GRGDSVSENG ETQKAGLVVP TSPKGKVLDR RSRSGKGRGL PKKGGAGGKG VWGTPGQVYD VEEVDIKDPN YDDDQENCVY ETVVLPLDER AFEKTLTPII QEYFEHGDTN EVSEMLKDLN LGEMKYSVPV LAVSLALEGK ASHREMTSKL ISDLCGTVVS KTDVEKSFDK LLKDLPDLVL DSPRAPQLVG QFIARAVGDG ILSSTYIDGY KGTVDSIQAR AALDRATVLL SVTKGGKRID NVWGSGGGQQ SVKHLVKEID MLLKEYLLSG DLLEAERCLQ ELEVPHFHHE LVYEAIVMVL ESTGEKTFKM MLDLLKSLSR SSVITMDQMK RGYERVYCEI PDINLDVPHS YSVLERFVEE CFQAGIISKP LRDLCPSRGR KRFVSEGDGG RLKPESY
  • 蛋白标签：
    Tag type will be determined during the manufacturing process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 产品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 复溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 储存条件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保质期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 货期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事项：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

产品评价

靶点详情

  • 功能：
    Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A and EIF4G. Inhibits the helicase activity of EIF4A. Binds RNA. Does not seem to be involved in apoptosis.
  • 基因功能参考文献：
    1. This work reveals a novel mechanism by which Pdcd4 affects the translation of cellular RNAs. PMID: 24681950
    2. c-myb mRNA as the first natural translational target mRNA of Pdcd4 PMID: 21643008
    3. Pdcd4 has an important function in the cellular response to DNA damage PMID: 19684621
  • 亚细胞定位：
    Nucleus. Cytoplasm. Note=Shuttles between the nucleus and cytoplasm. Predominantly nuclear under normal growth conditions.
  • 蛋白家族：
    PDCD4 family
  • 组织特异性：
    Expressed in a broad spectrum of hematopoietic organs, such as thymus and bursa. Lower levels of expression detected in the kidney.
  • 数据库链接：

    KEGG: gga:374191

    STRING: 9031.ENSGALP00000014143

    UniGene: Gga.4916