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ZBTB32 Antibody

  • 中文名称：
    ZBTB32兔多克隆抗体
  • 货号：
    CSB-PA897538LA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western blot
      All lanes: ZBTB32 antibody at 4μg/ml
      Lane 1: Mouse brain tissue
      Lane 2: Jurkat whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 53 kDa
      Observed band size: 53 kDa
    • Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA897538LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA897538LA01HU at dilution of 1:100
  • 其他：

产品详情

  • 产品描述：

    The ZBTB32 antibody was raised in rabbits against amino acids 1-294 of recombinant ZBTB32 protein. It exists as an unconjugated IgG isoform. Its purity is greater than 95% using protein G affinity chromatography purified.

    This ZBTB32 polyclonal antibody has undergone rigorous quality control in multiple applications, including ELISA, WB, and IHC. And it shows reactivity with human and mouse ZBTB32 protein. The ZBTB32 protein, also known as a repressor of estrogen receptor activity (REA), is a transcriptional regulator that plays a crucial role in various biological processes, including embryonic development, cell differentiation, and immune response.

  • 产品名称：
    Rabbit anti-Homo sapiens (Human) ZBTB32 Polyclonal antibody
  • Uniprot No.：
    Q9Y2Y4
  • 基因名：
    ZBTB32
  • 别名：
    FANCC interacting protein antibody; FANCC-interacting protein antibody; Fanconi anemia zinc finger protein antibody; FAXF antibody; FAZF antibody; OTTHUMP00000045790 antibody; repressor of GATA antibody; Rog antibody; Testis zinc finger protein antibody; ZBT32_HUMAN antibody; Zbtb32 antibody; ZBTB32 protein antibody; Zinc finger and BTB domain containing 32 antibody; Zinc finger and BTB domain-containing protein 32 antibody; Zinc finger protein 538 antibody; ZNF538 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human, Mouse
  • 免疫原：
    Recombinant Human Zinc finger and BTB domain-containing protein 32 protein (1-294AA)
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated

    本页面中的产品，ZBTB32 Antibody (CSB-PA897538LA01HU)，的标记方式是Non-conjugated。对于ZBTB32 Antibody，我们还提供其他标记。见下表：

    可提供标记
    标记方式 货号 产品名称 应用
    HRP CSB-PA897538LB01HU ZBTB32 Antibody, HRP conjugated ELISA
    FITC CSB-PA897538LC01HU ZBTB32 Antibody, FITC conjugated
    Biotin CSB-PA897538LD01HU ZBTB32 Antibody, Biotin conjugated ELISA
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    >95%, Protein G purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB, IHC
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:20-1:200
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    DNA-binding protein that binds to the to a 5'-TGTACAGTGT-3' core sequence. May function as a transcriptional transactivator and transcriptional repressor. Probably exerts its repressor effect by preventing GATA3 from binding to DNA. May play a role in regulating the differentiation and activation of helper T-cells.
  • 基因功能参考文献：
    1. ZBTB32 is a novel negative regulator of antibody recall responses. PMID: 27357154
    2. confirmed that the promyelocytic leukemia zinc finger (PLZF) BTB dimer is strand exchanged in solution, while the FAZF BTB dimer is not PMID: 20493880
    3. Here, it was shown that human endogenous retrovirus Rec can form a trimeric complex with TZFP and AR, and can relieve the TZFP-mediated repression of AR-induced transactivation. PMID: 20147518
    4. can interact with GATA-2 and can modify GATA-2 transactivation capacity PMID: 11964310
    5. results suggest an essential role for FAZF during the proliferative stages of primitive hematopoietic progenitors, possibly acting in concert with (a subset of) the Fanconi anemia proteins PMID: 11986317
    6. TZFP is identified as a novel BMP2-induced transcription factor during osteoblastic differentiation. PMID: 17171645

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  • 亚细胞定位：
    Nucleus. Note=Located in nuclear speckles.
  • 蛋白家族：
    Krueppel C2H2-type zinc-finger protein family
  • 组织特异性：
    Predominantly expressed in testis. Some isoforms are ubiquitously expressed.
  • 数据库链接：

    HGNC: 16763

    OMIM: 605859

    KEGG: hsa:27033

    STRING: 9606.ENSP00000262630

    UniGene: Hs.99430