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UBE2Z Antibody

  • 中文名称：
    UBE2Z兔多克隆抗体
  • 货号：
    CSB-PA025487GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q9H832
  • 基因名：
  • 别名：
    FLJ13855 antibody; GC17P044341 antibody; HOYS7 antibody; Uba6 specific E2 conjugating enzyme 1 antibody; UBA6 specific enzyme E2 antibody; Uba6-specific E2 conjugating enzyme 1 antibody; UBE2Z antibody; UBE2Z_HUMAN antibody; Ubiquitin carrier protein Z antibody; Ubiquitin conjugating enzyme E2 Z antibody; Ubiquitin conjugating enzyme E2Z antibody; Ubiquitin protein ligase Z antibody; Ubiquitin-conjugating enzyme E2 Z antibody; Ubiquitin-protein ligase Z antibody; Use1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human UBE2Z
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Catalyzes the covalent attachment of ubiquitin to other proteins. Specific substrate for UBA6, not charged with ubiquitin by UBE1. May be involved in apoptosis regulation.
  • 基因功能参考文献：
    1. The SNP rs46522 in UBE2Z gene is associated with the risk of coronary Artery disease in the individuals of Chinese Han descent with type 2 diabetes and is of synergistic effect with Body mass index. PMID: 28840129
    2. we found that USE1 proteins were frequently overexpressed in human lung cancer. Furthermore, overexpression of USE1 promoted in vivo and in vitro proliferation, migration, and invasion. PMID: 28376205
    3. Association of UBE2Z single nucleotide polymorphism rs46522 with the susceptibility to coronary artery disease in an Iranian population. PMID: 26602883
    4. UBE2Z was widely expressed in human tissues and is located on chromosome 17q21. PMID: 17160626
    5. In tissue culture cells, Uba6 is required for charging a previously uncharacterized Uba6-specific E2 (Use1), whereas Ube1 is required for charging the cell-cycle E2s Cdc34A and Cdc34B PMID: 17597759

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  • 亚细胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    Ubiquitin-conjugating enzyme family
  • 组织特异性：
    Widely expressed. Highly in placenta, pancreas, spleen and testis.
  • 数据库链接：

    HGNC: 25847

    OMIM: 611362

    KEGG: hsa:65264

    STRING: 9606.ENSP00000354201

    UniGene: Hs.514297