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TTYH2 Antibody

  • 中文名称：
    TTYH2多克隆抗体
  • 货号：
    CSB-PA871565XA01HU
  • 规格：
    ￥440
  • 促销：
    小规格抗体限时一口价
  • 图片：
    • Western Blot
      Positive WB detected in Recombinant protein
      All lanes: TTYH2 antibody at 1:2000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 22.88 kDa
      Observed band size: 28 kDa
  • 其他：

产品详情

  • Uniprot No.：
    Q9BSA4
  • 基因名：
    TTYH2
  • 别名：
    Protein tweety homolog 2 (hTTY2) TTYH2 C17orf29
  • 反应种属：
    Shigella flexneri
  • 免疫原：
    Recombinant Homo sapiens (Human) TTYH2 protein
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 克隆类型：
    Polyclonal
  • 抗体亚型：
    IgG
  • 纯化方式：
    Protein G
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA, WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Probable large-conductance Ca(2+)-activated chloride channel. May play a role in Ca(2+) signal transduction. May be involved in cell proliferation and cell aggregation.
  • 基因功能参考文献：
    1. TTYH2 gene expression is significantly up-regulated in colon cancer. The TTYH2 gene may play an important role in regulating both proliferating and metastatic potentials of colorectal cancer. PMID: 17569141
    2. N-glycosylation is not the determining factor for TTYH2 trafficking to the plasma membrane. PMID: 18260827
    3. expressed most highly in brain and testis and at lower levels in heart, ovary, spleen, and peripheral blood leukocytes. Expression of this gene is upregulated in 13 of 16 (81%) renal cell carcinoma samples examined PMID: 11597145
  • 亚细胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Tweety family
  • 组织特异性：
    Expressed at higher level in brain and testis and at lower levels in heart, ovary, spleen and peripheral blood leukocytes. Up-regulated in 13 of 16 renal cell carcinoma samples examined. Up-regulated in colon carcinoma.
  • 数据库链接：

    HGNC: 13877

    OMIM: 608855

    KEGG: hsa:94015

    STRING: 9606.ENSP00000269346

    UniGene: Hs.27935