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TBC1D21 Antibody

  • 中文名称:
    TBC1D21多克隆抗体
  • 货号:
    CSB-PA567895
  • 规格:
    ¥1100
  • 图片:
    • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Hepg2 cells, Primary antibody: CSB-PA567895(TBC1D21 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
  • 其他:

产品详情

  • Uniprot No.:
    Q8IYX1
  • 基因名:
    TBC1D21
  • 别名:
    TBC1D21 antibody; TBC1 domain family member 21 antibody
  • 宿主:
    Rabbit
  • 反应种属:
    Human
  • 免疫原:
    Synthetic peptide of Human TBC1D21
  • 免疫原种属:
    Homo sapiens (Human)
  • 标记方式:
    Non-conjugated
  • 抗体亚型:
    IgG
  • 纯化方式:
    Antigen affinity purification
  • 浓度:
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式:
    Liquid
  • 应用范围:
    ELISA,WB
  • 推荐稀释比:
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
  • Protocols:
  • 储存条件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能:
    May act as a GTPase-activating protein for Rab family protein(s). May be involved in acrosome formation and cytoskeletal reorganization during spermiogenesis, possibly by regulating RAB3A activity.
  • 基因功能参考文献:
    1. Data indicate that single-nucleotide polymorphisms (SNPs) distributing in not only lysyl oxidase-like 1 gene (LOXL1) but also TBC1 domain family member 21 protein (TBC1D21) and promyelocytic leukemia protein (PML). PMID: 24938310
    2. MgcRabGAP is involved in acrosome/acroplaxome formation and cytoskeletal reorganization via Rab activity during mammalian spermiogenesis PMID: 21128978
  • 亚细胞定位:
    Cytoplasmic vesicle, secretory vesicle, acrosome. Cytoplasm, cytoskeleton.
  • 组织特异性:
    Expressed in round and elongated spermatids (at protein level). Expressed specifically in adult testis and very weakly in fetal brain.
  • 数据库链接:

    HGNC: 28536

    KEGG: hsa:161514

    STRING: 9606.ENSP00000300504

    UniGene: Hs.124512