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RTFDC1 Antibody

  • 中文名称：
    RTFDC1兔多克隆抗体
  • 货号：
    CSB-PA003714GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q9BY42
  • 基因名：
    RTFDC1
  • 别名：
    RTF2 antibody; C20orf43 antibody; RTFDC1 antibody; AD-007 antibody; CDA05 antibody; HSPC164 antibody; HSPC169 antibody; Replication termination factor 2 antibody; RTF2 antibody; Replication termination factor 2 domain-containing protein 1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human C20orf43
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Replication termination factor which is a component of the elongating replisome. Required for ATR pathway signaling upon DNA damage and has a positive activity during DNA replication. Might function to facilitate fork pausing at replication fork barriers like the rDNA. May be globally required to stimulate ATR signaling after the fork stalls or encounters a lesion. Interacts with nascent DNA.
  • 基因功能参考文献：
    1. The results establish that RTF2 removal is a key determinant for the ability of cells to manage replication stress and maintain genome integrity. PMID: 29290612
  • 亚细胞定位：
    Chromosome.
  • 蛋白家族：
    Rtf2 family
  • 数据库链接：

    HGNC: 15890

    KEGG: hsa:51507

    STRING: 9606.ENSP00000023939

    UniGene: Hs.517134