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MUM1 Antibody

  • 货号：
    CSB-PA461204
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of mouse-kidney mouse-heart mouse-brain cells using MUM1 Polyclonal Antibody diluted at 1:1000. Secondary antibody was diluted at 1:20000
  • 其他：

产品详情

  • Uniprot No.：
    Q2TAK8
  • 基因名：
    MUM1
  • 别名：
    EXPAND1 antibody; FLJ14868 antibody; FLJ22283 antibody; HSPC211 antibody; Melanoma associated antigen (mutated) 1 antibody; Melanoma ubiquitous mutated protein antibody; MGC131891 antibody; MGC163315 antibody; MUM 1 antibody; MUM-1 antibody; MUM1 antibody; MUM1_HUMAN antibody; Mutated melanoma associated antigen 1 antibody; Mutated melanoma-associated antigen 1 antibody; Protein expandere antibody; PWWP domain containing protein MUM1 antibody; PWWP domain-containing protein MUM1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from MUM1 at AA range: 661-710
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB,ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-2000
    ELISA 1:10000-20000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage.
  • 基因功能参考文献：
    1. report the identification of the PWWP domain-containing protein EXPAND1/MUM1 as an architectural component of the chromatin, which in response to DNA damage serves as an accessory factor to promote cell survival. PMID: 20347427
  • 亚细胞定位：
    Nucleus. Note=Recruited to DNA damage sites via its interaction with the BRCT domain of TP53BP1.
  • 蛋白家族：
    MUM1 family
  • 数据库链接：

    HGNC: 29641

    KEGG: hsa:84939

    STRING: 9606.ENSP00000345789

    UniGene: Hs.515016