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  4. MSL3 Antibody

MSL3 Antibody

  • 中文名称：
    MSL3兔多克隆抗体
  • 货号：
    CSB-PA015042GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q8N5Y2
  • 基因名：
    MSL3
  • 别名：
    MSL3 antibody; AU018931 antibody; DKFZp586J1822 antibody; Drosophila MSL3 like 1 antibody; Male specific lethal 3 (Drosophila) like 1 antibody; Male specific lethal 3 homolog (Drosophila) antibody; Male specific lethal 3 homolog 1 (Drosophila) antibody; Male specific lethal 3 homolog 1 antibody; Male specific lethal 3 homolog antibody; Male specific lethal 3 like 1 (Drosophila) antibody; Male specific lethal 3 like 1 antibody; Male specific lethal 3 protein like 1 antibody; Male-specific lethal 3 homolog antibody; Male-specific lethal-3 homolog 1 antibody; Male-specific lethal-3 protein-like 1 antibody; MS3L1_HUMAN antibody; MSL3 antibody; MSL3 like 1 antibody; MSL3-like 1 antibody; Msl31 antibody; MSL3L1 antibody; OTTHUMP00000022911 antibody; OTTHUMP00000022912 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human MSL3
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity Purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Has a role in chromatin remodeling and transcriptional regulation. Has a role in X inactivation. Component of the MSL complex which is responsible for the majority of histone H4 acetylation at 'Lys-16' which is implicated in the formation of higher-order chromatin structure. Specifically recognizes histone H4 monomethylated at 'Lys-20' (H4K20Me1) in a DNA-dependent manner and is proposed to be involved in chromosomal targeting of the MSL complex.
  • 基因功能参考文献：
    1. MSL3 plays an important role in targeting the male specific lethal complex to chromatin in both humans and flies by binding to H4K20Me(1). PMID: 20943666
    2. A multisubunit human histone acetylase complex that contains homologs of the Drosophila MSL proteins MOF, MSL1 (hampin A), MSL2, and MSL3 was described. This complex is responsible for histone H4 lysine-16 acetylation of all cellular chromosomes. PMID: 16227571
  • 亚细胞定位：
    Nucleus.
  • 组织特异性：
    Expressed in many tissues including liver, pancreas, heart, lung, kidney, skeletal muscle, brain, and placenta, with highest expression in skeletal muscle and heart.
  • 数据库链接：

    HGNC: 7370

    OMIM: 300609

    KEGG: hsa:10943

    STRING: 9606.ENSP00000312244

    UniGene: Hs.655288