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HIGD1A Antibody

  • 中文名称：
    HIGD1A兔多克隆抗体
  • 货号：
    CSB-PA010354GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q9Y241
  • 基因名：
    HIGD1A
  • 别名：
    Hig1 antibody; HIG1 domain family member 1A antibody; HIG1 domain family; member 1A antibody; HIG1 hypoxia inducible domain family; member 1A antibody; HIG1A_HUMAN antibody; HIGD1A antibody; HIMP1 antibody; Hypoxia-inducible gene 1 protein antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human HIGD1A
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IF
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Proposed subunit of cytochrome c oxidase (COX, complex IV), which is the terminal component of the mitochondrial respiratory chain that catalyzes the reduction of oxygen to water. May play a role in the assembly of respiratory supercomplexes.
  • 基因功能参考文献：
    1. Nuclear localization of the mitochondrial factor HIGD1A during metabolic stress. PMID: 23646141
    2. Data indicate that hypoxia-induced gene domain protein-1a (Higd-1a) inhibits Optic atrophy 1 (Opa1) cleavage and is required for mitochondrial fusion by virtue of its interaction with Opa1. PMID: 23878241
    3. depletion of HIG1 increased gamma-secretase activation and enhanced hypoxia-induced mitochondrial dysfunction PMID: 22355194
  • 亚细胞定位：
    Mitochondrion membrane; Multi-pass membrane protein. Mitochondrion inner membrane.
  • 数据库链接：

    HGNC: 29527

    KEGG: hsa:25994

    STRING: 9606.ENSP00000398064

    UniGene: Hs.593134