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EVA1A Antibody

  • 中文名称：
    EVA1A兔多克隆抗体
  • 货号：
    CSB-PA222058
  • 规格：
    ￥1100
  • 图片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA222058(EVA1A Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA222058(EVA1A Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane: Human normal liver tissue, Primary antibody: CSB-PA222058(EVA1A Antibody) at dilution 1/550, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
  • 其他：

产品详情

  • Uniprot No.：
    Q9H8M9
  • 基因名：
    EVA1A
  • 别名：
    EVA1A; FAM176A; TMEM166; SP24; Protein eva-1 homolog A; Protein FAM176A; Transmembrane protein 166
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse
  • 免疫原：
    Synthetic peptide of Human EVA1A
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen affinity purification
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,WB,IHC
  • 推荐稀释比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
    IHC 1:25-1:100
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Acts as a regulator of programmed cell death, mediating both autophagy and apoptosis.
  • 基因功能参考文献：
    1. Low EVA1A expression is associated with glioblastoma. PMID: 28185834
    2. The adenovirus-mediated increase of FAM176A inhibited the growth of the tumor cells. PMID: 24257118
    3. TMEM166 expression was widely down-regulated in the cancer tissues. PMID: 22495369
    4. Low TMEM166 mRNA and protein expression is associated with esophageal squamous cell carcinoma. PMID: 23098460
    5. TMEM166 is a novel regulator involved in both autophagy and apoptosis. PMID: 17492404

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  • 亚细胞定位：
    Endoplasmic reticulum membrane; Single-pass membrane protein. Lysosome membrane; Single-pass membrane protein.
  • 蛋白家族：
    EVA1 family
  • 组织特异性：
    Expressed in lung, kidney, liver, pancreas, placenta, but not in heart and skeletal muscle.
  • 数据库链接：

    HGNC: 25816

    KEGG: hsa:84141

    STRING: 9606.ENSP00000233712

    UniGene: Hs.302346