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中文名称:DBP兔多克隆抗体
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货号:CSB-PA365892ZA01HIL
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规格:¥440
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促销:
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图片:
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其他:
产品详情
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产品描述:
The DBP polyclonal antibody is a rabbit-derived antibody that has been specifically designed to target the DBP protein. The immunogen used to generate this DBP antibody is a recombinant human adenovirus C serotype 5 DBP protein (174-529aa). The Adenovirus C Serotype 5 DBP is a key regulatory protein in the adenovirus DNA replication and packaging.
DBP mainly functions is to bind to the viral DNA and regulate the transcription of viral genes. It can interact with specific DNA sequences within the adenovirus genome and recruit other viral and cellular proteins to control the timing and efficiency of viral gene expression. This DBP antibody has been purified using protein A/G affinity chromatography. It has been validated for use in two applications, including ELISA and WB. And it shows reactivity with human adenovirus C serotype 5 samples.
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Uniprot No.:P03265
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基因名:
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别名:DNA-binding protein (DBP) (Early 2A protein) (Early E2A DNA-binding protein), DBP
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反应种属:Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)
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免疫原:Recombinant Human adenovirus C serotype 5 DNA-binding protein (DBP), partial (174-529AA)
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免疫原种属:Human adenovirus C serotype 5 (HAdV-5) (Human adenovirus 5)
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标记方式:Non-conjugated
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克隆类型:Polyclonal
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抗体亚型:IgG
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纯化方式:Protein G
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浓度:It differs from different batches. Please contact us to confirm it.
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保存缓冲液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 -
产品提供形式:Liquid
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应用范围:ELISA, WB
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Protocols:
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储存条件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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货期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
引用文献
- A novel role for the adenovirus L4 region 22K and 33K proteins in adeno-associated virus production A Adsero,Human gene therapy,2023
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靶点详情
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功能:Plays a role in the elongation phase of viral strand displacement replication by unwinding the template in an ATP-independent fashion, employing its capacity to form multimers. Also enhances the rate of initiation. Released from template upon second strand synthesis. Assembles in complex with viral pTP, viral pol, host NFIA and host POU2F1/OCT1 on viral origin of replication. Covers the whole ssDNA genome during synthesis. The complementary strand synthesis induces its relese from DNA template. May inhibit cellular transcription mediated by the interaction between host SRCAP and CBP.
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亚细胞定位:Host nucleus.
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蛋白家族:Adenoviridae E2A DNA-binding protein family
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