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DAPP1 Antibody

  • 中文名称：
    DAPP1兔多克隆抗体
  • 货号：
    CSB-PA006503GA01HU
  • 规格：
    ￥3,900
  • 其他：

产品详情

  • Uniprot No.：
    Q9UN19
  • 基因名：
  • 别名：
    B cell adapter molecule of 32 kDa antibody; B lymphocyte adapter protein Bam32 antibody; B-cell adapter molecule of 32 kDa antibody; BAM32 antibody; DAPP1 antibody; DAPP1_HUMAN antibody; DKFZp667E0716 antibody; Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide antibody; Dual adaptor of phosphotyrosine and 3 phosphoinositides antibody; hDAPP1 antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human,Mouse,Rat
  • 免疫原：
    Human DAPP1
  • 免疫原种属：
    Homo sapiens (Human)
  • 抗体亚型：
    IgG
  • 纯化方式：
    Antigen Affinity purified
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 产品提供形式：
    Liquid
  • 应用范围：
    ELISA,IHC,IF
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    May act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR)-signaling downstream of PI3K.
  • 基因功能参考文献：
    1. we propose a role for Bam32 in the signaling of MHC class I molecules in professional Ag-presenting DC for the regulation of CD8(+) T cell activation. PMID: 21930970
    2. novel phosphorylation-dependent function of Bam32 in regulating Rac1 activation and actin remodeling. PMID: 15247305
    3. BAM32 works downstream of Src family protein tyrosine kinases and functions to link B cell antigen receptor signals with antigen-processing pathways in B cells. PMID: 15494510
  • 亚细胞定位：
    Cytoplasm. Membrane; Peripheral membrane protein. Note=Membrane-associated after cell stimulation leading to its translocation.
  • 组织特异性：
    Highly expressed in placenta and lung, followed by brain, heart, kidney, liver, pancreas and skeletal muscle. Expressed by B-lymphocytes, but not T-lymphocytes or nonhematopoietic cells.
  • 数据库链接：

    HGNC: 16500

    OMIM: 605768

    KEGG: hsa:27071

    STRING: 9606.ENSP00000423602

    UniGene: Hs.436271