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COL5A3 Antibody

  • 货号：
    CSB-PA001753
  • 规格：
    ￥880
  • 图片：
    • Western Blot analysis of K562 cells using COL5A3 Polyclonal Antibody
    • Western Blot analysis of NIH-3T3 cells using COL5A3 Polyclonal Antibody
  • 其他：

产品详情

  • Uniprot No.：
    P25940
  • 基因名：
    COL5A3
  • 别名：
    COL5A3Collagen alpha-3(V) chain antibody
  • 宿主：
    Rabbit
  • 反应种属：
    Human
  • 免疫原：
    Synthesized peptide derived from the N-terminal region of Human COL5A3.
  • 免疫原种属：
    Homo sapiens (Human)
  • 标记方式：
    Non-conjugated
  • 抗体亚型：
    IgG
  • 纯化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度：
    It differs from different batches. Please contact us to confirm it.
  • 保存缓冲液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 产品提供形式：
    Liquid
  • 应用范围：
    WB, IHC, IF, ELISA
  • 推荐稀释比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    IF 1:200-1:1000
    ELISA 1:20000
  • Protocols：
  • 储存条件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 货期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

产品评价

靶点详情

  • 功能：
    Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V collagen binds to DNA, heparan sulfate, thrombospondin, heparin, and insulin.
  • 基因功能参考文献：
    1. analysis of processing of the Pro-alpha1(V)Pro-alpha2(V)Pro-alpha3(V) procollagen heterotrimer PMID: 15136578
    2. CBF/NF-Y and two repressors regulate the core promoter of the human pro-alpha3(V) collagen gene PMID: 15316020
    3. Absence of obvious disease-causing mutations and null alleles in a cohort of 13 patients with h-EDS is consistent with exclusion of COL5A3 as a candidate gene for this disease. PMID: 19012342
  • 亚细胞定位：
    Secreted, extracellular space, extracellular matrix.
  • 蛋白家族：
    Fibrillar collagen family
  • 数据库链接：

    HGNC: 14864

    OMIM: 120216

    KEGG: hsa:50509

    STRING: 9606.ENSP00000264828

    UniGene: Hs.235368