Tnfsf15
TNFSF15，也称为血管内皮生长抑制因子（VEGI）或TL1A，是由TNFSF15基因编码的蛋白质，位于染色体9q32上。该蛋白质由251个氨基酸组成，包含胞质结构域、跨膜域和胞外结构域，并能形成稳定的同源三聚体结构。TNFSF15主要作为死亡受体3（DR3）的配体，参与调控VEGF/VEGFR信号通路，影响内皮细胞的增殖、凋亡以及淋巴管生成等过程。它在血管生成、淋巴管形成、免疫调节等多个方面发挥重要作用，并为涉及血管通透性增加的病理过程（如肿瘤、脑卒中等）的治疗提供了新的靶点。
热销产品
验证数据
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity
Measured by its binding ability in a functional ELISA. Immobilized Human TNFSF15 at 2 μg/ml on streptavidin coated plates can bind Anti-TNFSF15 antibody (CSB-RA023992MA1HU). The EC50 is 0.2732 - 0.6370 ng/mL.
TNFSF15 Antibody (CSB-PA023992ESR2HU)
验证数据
Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA023992ESR2HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA023992ESR2HU at dilution of 1:100
Tnfsf15 Proteins
Tnfsf15 Proteins for Homo sapiens (Human)
| 产品货号 | 产品名称 | 来源 |
|---|---|---|
| CSB-MP023992HU(F2) | Recombinant Human Tumor necrosis factor ligand superfamily member 15(TNFSF15) (Active) | Mammalian cell |
| CSB-MP023992HU1-B | Recombinant Human Tumor necrosis factor ligand superfamily member 15(TNFSF15),partial,Biotinylated (Active) | Mammalian cell |
